HHSN272201700060C/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2018	16
2019	18
2020	43
2021	44
2022	20
2023	21
2024	6

1

Exploration of P1 and P4 modifications of nirmatrelvir: Design, synthesis, biological evaluation, and X-ray structural studies of SARS-CoV-2 Mpro inhibitors.

Ghosh AK, Yadav M, Iddum S, Ghazi S, Lendy EK, Jayashankar U, Beechboard SN, Takamatsu Y, Hattori SI, Aamano M, Higashi-Kuwata N, Mitsuya H, Mesecar AD. Ghosh AK, et al. Eur J Med Chem. 2024 Mar 5;267:116132. doi: 10.1016/j.ejmech.2024.116132. Epub 2024 Feb 1. Eur J Med Chem. 2024. PMID: 38335815

2

An acetyltransferase effector conserved across Legionella species targets the eukaryotic eIF3 complex to modulate protein translation.

Syriste L, Patel DT, Stogios PJ, Skarina T, Patel D, Savchenko A. Syriste L, et al. mBio. 2024 Mar 13;15(3):e0322123. doi: 10.1128/mbio.03221-23. Epub 2024 Feb 9. mBio. 2024. PMID: 38335095 Free PMC article.

3

Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.

Kim Y, Maltseva N, Tesar C, Jedrzejczak R, Endres M, Ma H, Dugan HL, Stamper CT, Chang C, Li L, Changrob S, Zheng NY, Huang M, Ramanathan A, Wilson P, Michalska K, Joachimiak A. Kim Y, et al. iScience. 2024 Jan 19;27(2):108976. doi: 10.1016/j.isci.2024.108976. eCollection 2024 Feb 16. iScience. 2024. PMID: 38327783 Free PMC article.

4

Biochemical and Structural Analysis of the Bacterial Enzyme Succinyl-Diaminopimelate Desuccinylase (DapE) from Acinetobacter baumannii.

Kelley EH, Minasov G, Konczak K, Shuvalova L, Brunzelle JS, Shukla S, Beulke M, Thabthimthong T, Olsen KW, Inniss NL, Satchell KJF, Becker DP. Kelley EH, et al. ACS Omega. 2024 Jan 8;9(3):3905-3915. doi: 10.1021/acsomega.3c08231. eCollection 2024 Jan 23. ACS Omega. 2024. PMID: 38284080 Free PMC article.

5

Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus.

Adams LJ, Raju S, Ma H, Gilliland T Jr, Reed DS, Klimstra WB, Fremont DH, Diamond MS. Adams LJ, et al. Cell. 2024 Jan 18;187(2):360-374.e19. doi: 10.1016/j.cell.2023.11.031. Epub 2024 Jan 3. Cell. 2024. PMID: 38176410

6

Immunoglobulin replacement products protect against SARS-CoV-2 infection in vivo despite poor neutralizing activity.

Zimmerman O, Altman Doss AM, Ying B, Liang CY, Mackin SR, Davis-Adams HG, Adams LJ, VanBlargan LA, Chen RE, Scheaffer SM, Desai P, Raju S, Mantia TL, O'Shaughnessy CC, Monroy JM, Wedner HJ, Rigell CJ, Kau AL, Dy TB, Ren Z, Turner JS, O'Halloran JA, Presti RM, Kendall PL, Fremont DH, Ellebedy AH, Diamond MS. Zimmerman O, et al. JCI Insight. 2024 Feb 8;9(3):e176359. doi: 10.1172/jci.insight.176359. JCI Insight. 2024. PMID: 38175703 Free PMC article.

7

Control of Biofilm Formation by an Agrobacterium tumefaciens Pterin-Binding Periplasmic Protein Conserved Among Pathogenic Bacteria.

Greenwich JL, Eagan JL, Feirer N, Boswinkle K, Minasov G, Shuvalova L, Inniss NL, Raghavaiah J, Ghosh AK, Satchell KJF, Allen KD, Fuqua C. Greenwich JL, et al. bioRxiv [Preprint]. 2023 Nov 21:2023.11.18.567607. doi: 10.1101/2023.11.18.567607. bioRxiv. 2023. PMID: 38014264 Free PMC article. Preprint.

8

Structural and functional basis of VLDLR receptor usage by Eastern equine encephalitis virus.

Adams LJ, Raju S, Ma H, Gilliland T Jr, Reed DS, Klimstra WB, Fremont DH, Diamond MS. Adams LJ, et al. bioRxiv [Preprint]. 2023 Nov 15:2023.11.15.567188. doi: 10.1101/2023.11.15.567188. bioRxiv. 2023. PMID: 38014196 Free PMC article. Updated. Preprint.

9

Functional diversification despite structural congruence in the HipBST toxin-antitoxin system of Legionella pneumophila.

Lin JD, Stogios PJ, Abe KT, Wang A, MacPherson J, Skarina T, Gingras A-C, Savchenko A, Ensminger AW. Lin JD, et al. mBio. 2023 Oct 31;14(5):e0151023. doi: 10.1128/mbio.01510-23. Epub 2023 Oct 11. mBio. 2023. PMID: 37819088 Free PMC article.

10

Vertebrate-class-specific binding modes of the alphavirus receptor MXRA8.

Zimmerman O, Zimmerman MI, Raju S, Nelson CA, Errico JM, Madden EA, Holmes AC, Hassan AO, VanBlargan LA, Kim AS, Adams LJ, Basore K, Whitener BM, Palakurty S, Davis-Adams HG, Sun C, Gilliland T Jr, Earnest JT, Ma H, Ebel GD, Zmasek C, Scheuermann RH, Klimstra WB, Fremont DH, Diamond MS. Zimmerman O, et al. Cell. 2023 Oct 26;186(22):4818-4833.e25. doi: 10.1016/j.cell.2023.09.007. Epub 2023 Oct 6. Cell. 2023. PMID: 37804831

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