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Clinical validation of a quantitative HIV-1 DNA droplet digital PCR assay: Applications for detecting occult HIV-1 infection and monitoring cell-associated HIV-1 dynamics across different subtypes in HIV-1 prevention and cure trials.
Powell L, Dhummakupt A, Siems L, Singh D, Le Duff Y, Uprety P, Jennings C, Szewczyk J, Chen Y, Nastouli E, Persaud D. Powell L, et al. J Clin Virol. 2021 Jun;139:104822. doi: 10.1016/j.jcv.2021.104822. Epub 2021 Apr 14. J Clin Virol. 2021. PMID: 33930698 Free PMC article.
Multi-Laboratory Comparison of Next-Generation to Sanger-Based Sequencing for HIV-1 Drug Resistance Genotyping.
Parkin NT, Avila-Rios S, Bibby DF, Brumme CJ, Eshleman SH, Harrigan PR, Howison M, Hunt G, Ji H, Kantor R, Ledwaba J, Lee ER, Matías-Florentino M, Mbisa JL, Noguera-Julian M, Paredes R, Rivera-Amill V, Swanstrom R, Zaccaro DJ, Zhang Y, Zhou S, Jennings C. Parkin NT, et al. Viruses. 2020 Jun 27;12(7):694. doi: 10.3390/v12070694. Viruses. 2020. PMID: 32605062 Free PMC article.
Use of External Quality Control Material for HIV-1 RNA Testing To Assess the Comparability of Data Generated in Separate Laboratories and the Stability of HIV-1 RNA in Samples after Prolonged Storage.
Jennings C, Wager CG, Scianna SR, Zaccaro DJ, Couzens A, Mellors JW, Coombs RW, Bremer JW. Jennings C, et al. J Clin Microbiol. 2018 May 25;56(6):e00120-18. doi: 10.1128/JCM.00120-18. Print 2018 Jun. J Clin Microbiol. 2018. PMID: 29618501 Free PMC article. Clinical Trial.
Novel Assays for Measurement of Total Cell-Associated HIV-1 DNA and RNA.
Hong F, Aga E, Cillo AR, Yates AL, Besson G, Fyne E, Koontz DL, Jennings C, Zheng L, Mellors JW. Hong F, et al. J Clin Microbiol. 2016 Apr;54(4):902-11. doi: 10.1128/JCM.02904-15. Epub 2016 Jan 13. J Clin Microbiol. 2016. PMID: 26763968 Free PMC article.
Comparison of Three Different FDA-Approved Plasma HIV-1 RNA Assay Platforms Confirms the Virologic Failure Endpoint of 200 Copies per Milliliter Despite Improved Assay Sensitivity.
Lalama CM, Jennings C, Johnson VA, Coombs RW, McKinnon JE, Bremer JW, Cobb BR, Cloherty GA, Mellors JW, Ribaudo HJ; AIDS Clinical Trials Group. Lalama CM, et al. J Clin Microbiol. 2015 Aug;53(8):2659-66. doi: 10.1128/JCM.00801-15. Epub 2015 Jun 10. J Clin Microbiol. 2015. PMID: 26063861 Free PMC article.