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Pharmacokinetic and pharmacodynamic evaluation of the atypical tetracyclines chelocardin and amidochelocardin in murine infection models.
Rox K, Jansen R, Lukežič T, Greweling-Pils M, Herrmann J, Miethke M, Hüttel S, Hennessen F, Abou Fayad A, Holzhausen C, Lundberg CV, Teague J, Sudarman E, Bülter L, Hesterkamp T, Stadler M, Brönstrup M, Müller R. Rox K, et al. Among authors: huttel s. Microbiol Spectr. 2024 Jan 11;12(1):e0128923. doi: 10.1128/spectrum.01289-23. Epub 2023 Dec 4. Microbiol Spectr. 2024. PMID: 38047701 Free PMC article.
ER-dependent membrane repair of mycobacteria-induced vacuole damage.
Anand A, Mazur A-C, Rosell-Arevalo P, Franzkoch R, Breitsprecher L, Listian SA, Hüttel SV, Müller D, Schäfer DG, Vormittag S, Hilbi H, Maniak M, Gutierrez MG, Barisch C. Anand A, et al. Among authors: huttel sv. mBio. 2023 Oct 31;14(5):e0094323. doi: 10.1128/mbio.00943-23. Epub 2023 Sep 7. mBio. 2023. PMID: 37676004 Free PMC article.
Revision of the Absolute Configurations of Chelocardin and Amidochelocardin.
Sikandar A, Popoff A, Jumde RP, Mándi A, Kaur A, Elgaher WAM, Rosenberger L, Hüttel S, Jansen R, Hunter M, Köhnke J, Hirsch AKH, Kurtán T, Müller R. Sikandar A, et al. Among authors: huttel s. Angew Chem Int Ed Engl. 2023 Oct 2;62(40):e202306437. doi: 10.1002/anie.202306437. Epub 2023 Aug 17. Angew Chem Int Ed Engl. 2023. PMID: 37466921
Corallopyronin A: antimicrobial discovery to preclinical development.
Krome AK, Becker T, Kehraus S, Schiefer A, Gütschow M, Chaverra-Muñoz L, Hüttel S, Jansen R, Stadler M, Ehrens A, Pogorevc D, Müller R, Hübner MP, Hesterkamp T, Pfarr K, Hoerauf A, Wagner KG, König GM. Krome AK, et al. Among authors: huttel s. Nat Prod Rep. 2022 Sep 21;39(9):1705-1720. doi: 10.1039/d2np00012a. Nat Prod Rep. 2022. PMID: 35730490 Review.
Regio- and Stereoselective Epoxidation and Acidic Epoxide Opening of Antibacterial and Antiplasmodial Chlorotonils Yield Highly Potent Derivatives.
Hofer W, Oueis E, Fayad AA, Deschner F, Andreas A, de Carvalho LP, Hüttel S, Bernecker S, Pätzold L, Morgenstern B, Zaburannyi N, Bischoff M, Stadler M, Held J, Herrmann J, Müller R. Hofer W, et al. Among authors: huttel s. Angew Chem Int Ed Engl. 2022 Jul 25;61(30):e202202816. doi: 10.1002/anie.202202816. Epub 2022 Jun 13. Angew Chem Int Ed Engl. 2022. PMID: 35485800 Free PMC article.
32 results