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Discovery of the Lanthipeptide Curvocidin and Structural Insights into its Trifunctional Synthetase CuvL.
Sigurdsson A, Martins BM, Düttmann SA, Jasyk M, Dimos-Röhl B, Schöpf F, Gemander M, Knittel CH, Schnegotzki R, Schmid B, Kosol S, Pommerening L, Gonzáles-Viegaz M, Seidel M, Hügelland M, Leimkühler S, Dobbek H, Mainz A, Süssmuth RD. Sigurdsson A, et al. Among authors: hugelland m. Angew Chem Int Ed Engl. 2023 Jun 5;62(23):e202302490. doi: 10.1002/anie.202302490. Epub 2023 Apr 27. Angew Chem Int Ed Engl. 2023. PMID: 37014271
The gyrase inhibitor albicidin consists of p-aminobenzoic acids and cyanoalanine.
Cociancich S, Pesic A, Petras D, Uhlmann S, Kretz J, Schubert V, Vieweg L, Duplan S, Marguerettaz M, Noëll J, Pieretti I, Hügelland M, Kemper S, Mainz A, Rott P, Royer M, Süssmuth RD. Cociancich S, et al. Among authors: hugelland m. Nat Chem Biol. 2015 Mar;11(3):195-7. doi: 10.1038/nchembio.1734. Epub 2015 Jan 19. Nat Chem Biol. 2015. PMID: 25599532
Genome mining reveals the genus Xanthomonas to be a promising reservoir for new bioactive non-ribosomally synthesized peptides.
Royer M, Koebnik R, Marguerettaz M, Barbe V, Robin GP, Brin C, Carrere S, Gomez C, Hügelland M, Völler GH, Noëll J, Pieretti I, Rausch S, Verdier V, Poussier S, Rott P, Süssmuth RD, Cociancich S. Royer M, et al. Among authors: hugelland m. BMC Genomics. 2013 Sep 27;14:658. doi: 10.1186/1471-2164-14-658. BMC Genomics. 2013. PMID: 24069909 Free PMC article.