Hüfner A - Search Results

1

Synthesis and antibacterial evaluation of a new series of N-Alkyl-2-alkynyl/(E)-alkenyl-4-(1H)-quinolones.

Wube A, Guzman JD, Hüfner A, Hochfellner C, Blunder M, Bauer R, Gibbons S, Bhakta S, Bucar F. Wube A, et al. Among authors: hufner a. Molecules. 2012 Jul 9;17(7):8217-40. doi: 10.3390/molecules17078217. Molecules. 2012. PMID: 22777190 Free PMC article.

2

Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl-4(1H)-quinolones.

Wube AA, Hüfner A, Thomaschitz C, Blunder M, Kollroser M, Bauer R, Bucar F. Wube AA, et al. Among authors: hufner a. Bioorg Med Chem. 2011 Jan 1;19(1):567-79. doi: 10.1016/j.bmc.2010.10.060. Epub 2010 Nov 3. Bioorg Med Chem. 2011. PMID: 21106378 Free PMC article.

3

Synthesis of N-substituted 2-[(1E)-alkenyl]-4-(1H)-quinolone derivatives as antimycobacterial agents against non-tubercular mycobacteria.

Wube AA, Bucar F, Hochfellner C, Blunder M, Bauer R, Hüfner A. Wube AA, et al. Among authors: hufner a. Eur J Med Chem. 2011 Jun;46(6):2091-101. doi: 10.1016/j.ejmech.2011.02.062. Epub 2011 Mar 3. Eur J Med Chem. 2011. PMID: 21429630 Free PMC article.

4

1,2-substituted 4-(1H)-quinolones: synthesis, antimalarial and antitrypanosomal activities in vitro.

Wube A, Hüfner A, Seebacher W, Kaiser M, Brun R, Bauer R, Bucar F. Wube A, et al. Among authors: hufner a. Molecules. 2014 Sep 10;19(9):14204-20. doi: 10.3390/molecules190914204. Molecules. 2014. PMID: 25211002 Free PMC article.

5

Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics.

Guzman JD, Wube A, Evangelopoulos D, Gupta A, Hüfner A, Basavannacharya C, Rahman MM, Thomaschitz C, Bauer R, McHugh TD, Nobeli I, Prieto JM, Gibbons S, Bucar F, Bhakta S. Guzman JD, et al. Among authors: hufner a. J Antimicrob Chemother. 2011 Aug;66(8):1766-72. doi: 10.1093/jac/dkr203. Epub 2011 May 28. J Antimicrob Chemother. 2011. PMID: 21622974 Free PMC article.

6

Synthesis of Novel Shikonin Derivatives and Pharmacological Effects of Cyclopropylacetylshikonin on Melanoma Cells.

Durchschein C, Hufner A, Rinner B, Stallinger A, Deutsch A, Lohberger B, Bauer R, Kretschmer N. Durchschein C, et al. Among authors: hufner a. Molecules. 2018 Oct 30;23(11):2820. doi: 10.3390/molecules23112820. Molecules. 2018. PMID: 30380765 Free PMC article.

7

Derivatives of schisandrin with increased inhibitory potential on prostaglandin E(2) and leukotriene B(4) formation in vitro.

Blunder M, Pferschy-Wenzig EM, Fabian WM, Hüfner A, Kunert O, Saf R, Schühly W, Bauer R. Blunder M, et al. Among authors: hufner a. Bioorg Med Chem. 2010 Apr 1;18(7):2809-15. doi: 10.1016/j.bmc.2009.10.031. Epub 2009 Oct 20. Bioorg Med Chem. 2010. PMID: 20236826

8

Synthesis and Pharmacological In Vitro Investigations of Novel Shikonin Derivatives with a Special Focus on Cyclopropane Bearing Derivatives.

Kretschmer N, Hufner A, Durchschein C, Popodi K, Rinner B, Lohberger B, Bauer R. Kretschmer N, et al. Among authors: hufner a. Int J Mol Sci. 2021 Mar 9;22(5):2774. doi: 10.3390/ijms22052774. Int J Mol Sci. 2021. PMID: 33803437 Free PMC article.

9

SK119, a Novel Shikonin Derivative, Leads to Apoptosis in Melanoma Cell Lines and Exhibits Synergistic Effects with Vemurafenib and Cobimetinib.

Kretschmer N, Durchschein C, Hufner A, Rinner B, Lohberger B, Bauer R. Kretschmer N, et al. Among authors: hufner a. Int J Mol Sci. 2022 May 19;23(10):5684. doi: 10.3390/ijms23105684. Int J Mol Sci. 2022. PMID: 35628494 Free PMC article.

10

Design and synthesis of ten biphenyl-neolignan derivatives and their in vitro inhibitory potency against cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated LTB4-formation.

Schühly W, Hüfner A, Pferschy-Wenzig EM, Prettner E, Adams M, Bodensieck A, Kunert O, Oluwemimo A, Haslinger E, Bauer R. Schühly W, et al. Among authors: hufner a. Bioorg Med Chem. 2009 Jul 1;17(13):4459-65. doi: 10.1016/j.bmc.2009.05.018. Epub 2009 May 18. Bioorg Med Chem. 2009. PMID: 19481465

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