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Structure-Activity Relationship Explorations and Discovery of a Potent Antagonist for the Free Fatty Acid Receptor 2.
ChemMedChem. 2021 Nov 5;16(21):3326-3341. doi: 10.1002/cmdc.202100356. Epub 2021 Sep 12.
ChemMedChem. 2021.
PMID: 34288488
The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment.
Björkman L, Mårtensson J, Winther M, Gabl M, Holdfeldt A, Uhrbom M, Bylund J, Højgaard Hansen A, Pandey SK, Ulven T, Forsman H, Dahlgren C.
Björkman L, et al. Among authors: hojgaard hansen a.
Mol Cell Biol. 2016 Sep 26;36(20):2583-95. doi: 10.1128/MCB.00161-16. Print 2016 Oct 15.
Mol Cell Biol. 2016.
PMID: 27503855
Free PMC article.
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Discovery of Potent Tetrazole Free Fatty Acid Receptor 2 Antagonists.
Valentini A, Schultz-Knudsen K, Højgaard Hansen A, Tsakoumagkou A, Jenkins L, Christensen HB, Manandhar A, Milligan G, Ulven T, Rexen Ulven E.
Valentini A, et al. Among authors: hojgaard hansen a.
J Med Chem. 2023 May 11;66(9):6105-6121. doi: 10.1021/acs.jmedchem.2c01935. Epub 2023 May 2.
J Med Chem. 2023.
PMID: 37129317
Free PMC article.
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