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The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection.
Dieudé M, Bell C, Turgeon J, Beillevaire D, Pomerleau L, Yang B, Hamelin K, Qi S, Pallet N, Béland C, Dhahri W, Cailhier JF, Rousseau M, Duchez AC, Lévesque T, Lau A, Rondeau C, Gingras D, Muruve D, Rivard A, Cardinal H, Perreault C, Desjardins M, Boilard É, Thibault P, Hébert MJ. Dieudé M, et al. Among authors: hebert mj. Sci Transl Med. 2015 Dec 16;7(318):318ra200. doi: 10.1126/scitranslmed.aac9816. Sci Transl Med. 2015. PMID: 26676607
Platelet EVs contain an active proteasome involved in protein processing for antigen presentation via MHC-I molecules.
Marcoux G, Laroche A, Hasse S, Bellio M, Mbarik M, Tamagne M, Allaeys I, Zufferey A, Lévesque T, Rebetz J, Karakeussian-Rimbaud A, Turgeon J, Bourgoin SG, Hamzeh-Cognasse H, Cognasse F, Kapur R, Semple JW, Hébert MJ, Pirenne F, Overkleeft HS, Florea BI, Dieude M, Vingert B, Boilard E. Marcoux G, et al. Among authors: hebert mj. Blood. 2021 Dec 23;138(25):2607-2620. doi: 10.1182/blood.2020009957. Blood. 2021. PMID: 34293122 Free article.
Hypothermic Perfusion Modifies the Association Between Anti-LG3 Antibodies and Delayed Graft Function in Kidney Recipients.
Mawad H, Pinard L, Medani S, Chagnon M, Boucquemont J, Turgeon J, Dieudé M, Hamelin K, Rimbaud AK, Belayachi A, Yang B, Collette S, Sénécal L, Foster BJ, Hébert MJ, Cardinal H. Mawad H, et al. Among authors: hebert mj. Transpl Int. 2023 Feb 20;36:10749. doi: 10.3389/ti.2023.10749. eCollection 2023. Transpl Int. 2023. PMID: 36891519 Free PMC article.
Autophagy drives fibroblast senescence through MTORC2 regulation.
Bernard M, Yang B, Migneault F, Turgeon J, Dieudé M, Olivier MA, Cardin GB, El-Diwany M, Underwood K, Rodier F, Hébert MJ. Bernard M, et al. Among authors: hebert mj. Autophagy. 2020 Nov;16(11):2004-2016. doi: 10.1080/15548627.2020.1713640. Epub 2020 Jan 13. Autophagy. 2020. PMID: 31931659 Free PMC article.
Autophagy, tissue repair, and fibrosis: a delicate balance.
Migneault F, Hébert MJ. Migneault F, et al. Among authors: hebert mj. Matrix Biol. 2021 Jun;100-101:182-196. doi: 10.1016/j.matbio.2021.01.003. Epub 2021 Jan 14. Matrix Biol. 2021. PMID: 33454422 Review.
142 results