Hämäläinen RH - Search Results

1

Mitochondria and mtDNA integrity in stem cell function and differentiation.

Hämäläinen RH. Hämäläinen RH. Curr Opin Genet Dev. 2016 Jun;38:83-89. doi: 10.1016/j.gde.2016.04.008. Epub 2016 May 21. Curr Opin Genet Dev. 2016. PMID: 27219871 Review.

2

Induced pluripotent stem cell-derived models for mtDNA diseases.

Hämäläinen RH. Hämäläinen RH. Methods Enzymol. 2014;547:399-415. doi: 10.1016/B978-0-12-801415-8.00019-9. Methods Enzymol. 2014. PMID: 25416367

3

Stem cells, mitochondria and aging.

Ahlqvist KJ, Suomalainen A, Hämäläinen RH. Ahlqvist KJ, et al. Among authors: hamalainen rh. Biochim Biophys Acta. 2015 Nov;1847(11):1380-6. doi: 10.1016/j.bbabio.2015.05.014. Epub 2015 May 23. Biochim Biophys Acta. 2015. PMID: 26014347 Free article. Review.

4

mtDNA Mutagenesis Disrupts Pluripotent Stem Cell Function by Altering Redox Signaling.

Hämäläinen RH, Ahlqvist KJ, Ellonen P, Lepistö M, Logan A, Otonkoski T, Murphy MP, Suomalainen A. Hämäläinen RH, et al. Cell Rep. 2015 Jun 16;11(10):1614-24. doi: 10.1016/j.celrep.2015.05.009. Epub 2015 May 28. Cell Rep. 2015. PMID: 26027936 Free PMC article.

5

Generation and Characterization of Induced Pluripotent Stem Cells from Patients with mtDNA Mutations.

Hämäläinen RH, Suomalainen A. Hämäläinen RH, et al. Methods Mol Biol. 2016;1353:65-75. doi: 10.1007/7651_2015_258. Methods Mol Biol. 2016. PMID: 26187202

6

Mitochondrial DNA mutations in iPS cells: mtDNA integrity as standard iPSC selection criteria?

Hämäläinen RH. Hämäläinen RH. EMBO J. 2016 Sep 15;35(18):1960-2. doi: 10.15252/embj.201695185. Epub 2016 Jul 28. EMBO J. 2016. PMID: 27469999 Free PMC article.

7

Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy.

Latorre-Pellicer A, Lechuga-Vieco AV, Johnston IG, Hämäläinen RH, Pellico J, Justo-Méndez R, Fernández-Toro JM, Clavería C, Guaras A, Sierra R, Llop J, Torres M, Criado LM, Suomalainen A, Jones NS, Ruíz-Cabello J, Enríquez JA. Latorre-Pellicer A, et al. Among authors: hamalainen rh. Cell Metab. 2019 Dec 3;30(6):1120-1130.e5. doi: 10.1016/j.cmet.2019.09.007. Epub 2019 Oct 3. Cell Metab. 2019. PMID: 31588014 Free PMC article.

8

Defects in mtDNA replication challenge nuclear genome stability through nucleotide depletion and provide a unifying mechanism for mouse progerias.

Hämäläinen RH, Landoni JC, Ahlqvist KJ, Goffart S, Ryytty S, Rahman MO, Brilhante V, Icay K, Hautaniemi S, Wang L, Laiho M, Suomalainen A. Hämäläinen RH, et al. Nat Metab. 2019 Oct;1(10):958-965. doi: 10.1038/s42255-019-0120-1. Epub 2019 Oct 7. Nat Metab. 2019. PMID: 32694840

9

Somatic progenitor cell vulnerability to mitochondrial DNA mutagenesis underlies progeroid phenotypes in Polg mutator mice.

Ahlqvist KJ, Hämäläinen RH, Yatsuga S, Uutela M, Terzioglu M, Götz A, Forsström S, Salven P, Angers-Loustau A, Kopra OH, Tyynismaa H, Larsson NG, Wartiovaara K, Prolla T, Trifunovic A, Suomalainen A. Ahlqvist KJ, et al. Among authors: hamalainen rh. Cell Metab. 2012 Jan 4;15(1):100-9. doi: 10.1016/j.cmet.2011.11.012. Cell Metab. 2012. PMID: 22225879 Free article.

10

Tissue- and cell-type-specific manifestations of heteroplasmic mtDNA 3243A>G mutation in human induced pluripotent stem cell-derived disease model.

Hämäläinen RH, Manninen T, Koivumäki H, Kislin M, Otonkoski T, Suomalainen A. Hämäläinen RH, et al. Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):E3622-30. doi: 10.1073/pnas.1311660110. Epub 2013 Sep 3. Proc Natl Acad Sci U S A. 2013. PMID: 24003133 Free PMC article.

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