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Novel Orthogonally Hydrocarbon-Modified Cell-Penetrating Peptide Nanoparticles Mediate Efficient Delivery of Splice-Switching Antisense Oligonucleotides In Vitro and In Vivo.
Bazaz S, Lehto T, Tops R, Gissberg O, Gupta D, Bestas B, Bost J, Wiklander OPB, Sork H, Zaghloul EM, Mamand DR, Hällbrink M, Sillard R, Saher O, Ezzat K, Smith CIE, Andaloussi SE, Lehto T. Bazaz S, et al. Among authors: hallbrink m. Biomedicines. 2021 Aug 19;9(8):1046. doi: 10.3390/biomedicines9081046. Biomedicines. 2021. PMID: 34440250 Free PMC article.
Efficient Peptide-Mediated In Vitro Delivery of Cas9 RNP.
Gustafsson O, Rädler J, Roudi S, Lehto T, Hällbrink M, Lehto T, Gupta D, Andaloussi SE, Nordin JZ. Gustafsson O, et al. Among authors: hallbrink m. Pharmaceutics. 2021 Jun 14;13(6):878. doi: 10.3390/pharmaceutics13060878. Pharmaceutics. 2021. PMID: 34198625 Free PMC article.
Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency.
Sork H, Nordin JZ, Turunen JJ, Wiklander OP, Bestas B, Zaghloul EM, Margus H, Padari K, Duru AD, Corso G, Bost J, Vader P, Pooga M, Smith CE, Wood MJ, Schiffelers RM, Hällbrink M, Andaloussi SE. Sork H, et al. Among authors: hallbrink m. Mol Ther Nucleic Acids. 2016 Mar 8;5(3):e290. doi: 10.1038/mtna.2016.8. Mol Ther Nucleic Acids. 2016. PMID: 27111416 Free PMC article.
PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation.
Ezzat K, Andaloussi SE, Zaghloul EM, Lehto T, Lindberg S, Moreno PM, Viola JR, Magdy T, Abdo R, Guterstam P, Sillard R, Hammond SM, Wood MJ, Arzumanov AA, Gait MJ, Smith CI, Hällbrink M, Langel Ü. Ezzat K, et al. Among authors: hallbrink m. Nucleic Acids Res. 2011 Jul;39(12):5284-98. doi: 10.1093/nar/gkr072. Epub 2011 Feb 23. Nucleic Acids Res. 2011. PMID: 21345932 Free PMC article.
CTG repeat-targeting oligonucleotides for down-regulating Huntingtin expression.
Zaghloul EM, Gissberg O, Moreno PMD, Siggens L, Hällbrink M, Jørgensen AS, Ekwall K, Zain R, Wengel J, Lundin KE, Smith CIE. Zaghloul EM, et al. Among authors: hallbrink m. Nucleic Acids Res. 2017 May 19;45(9):5153-5169. doi: 10.1093/nar/gkx111. Nucleic Acids Res. 2017. PMID: 28334749 Free PMC article.
Role of autophagy in cell-penetrating peptide transfection model.
Dowaidar M, Gestin M, Cerrato CP, Jafferali MH, Margus H, Kivistik PA, Ezzat K, Hallberg E, Pooga M, Hällbrink M, Langel Ü. Dowaidar M, et al. Among authors: hallbrink m. Sci Rep. 2017 Oct 3;7(1):12635. doi: 10.1038/s41598-017-12747-z. Sci Rep. 2017. PMID: 28974718 Free PMC article.
Simultaneous membrane interaction of amphipathic peptide monomers, self-aggregates and cargo complexes detected by fluorescence correlation spectroscopy.
Vasconcelos L, Lehto T, Madani F, Radoi V, Hällbrink M, Vukojević V, Langel Ü. Vasconcelos L, et al. Among authors: hallbrink m. Biochim Biophys Acta Biomembr. 2018 Feb;1860(2):491-504. doi: 10.1016/j.bbamem.2017.09.024. Epub 2017 Sep 28. Biochim Biophys Acta Biomembr. 2018. PMID: 28962904 Free article.
Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties.
Nordin JZ, Lee Y, Vader P, Mäger I, Johansson HJ, Heusermann W, Wiklander OP, Hällbrink M, Seow Y, Bultema JJ, Gilthorpe J, Davies T, Fairchild PJ, Gabrielsson S, Meisner-Kober NC, Lehtiö J, Smith CI, Wood MJ, El Andaloussi S. Nordin JZ, et al. Among authors: hallbrink m. Nanomedicine. 2015 May;11(4):879-83. doi: 10.1016/j.nano.2015.01.003. Epub 2015 Feb 4. Nanomedicine. 2015. PMID: 25659648 Free article.
50 results