Häge S - Search Results

1

Methodological Development of a Multi-Readout Assay for the Assessment of Antiviral Drugs against SARS-CoV-2.

Hahn F, Häge S, Herrmann A, Wangen C, Kicuntod J, Jungnickl D, Tillmanns J, Müller R, Fraedrich K, Überla K, Kohlhof H, Ensser A, Marschall M. Hahn F, et al. Among authors: hage s. Pathogens. 2021 Aug 25;10(9):1076. doi: 10.3390/pathogens10091076. Pathogens. 2021. PMID: 34578109 Free PMC article.

2

Protein kinases responsible for the phosphorylation of the nuclear egress core complex of human cytomegalovirus.

Sonntag E, Milbradt J, Svrlanska A, Strojan H, Häge S, Kraut A, Hesse AM, Amin B, Sonnewald U, Couté Y, Marschall M. Sonntag E, et al. Among authors: hage s. J Gen Virol. 2017 Oct;98(10):2569-2581. doi: 10.1099/jgv.0.000931. Epub 2017 Sep 27. J Gen Virol. 2017. PMID: 28949903

3

High-resolution crystal structures of two prototypical β- and γ-herpesviral nuclear egress complexes unravel the determinants of subfamily specificity.

Muller YA, Häge S, Alkhashrom S, Höllriegl T, Weigert S, Dolles S, Hof K, Walzer SA, Egerer-Sieber C, Conrad M, Holst S, Lösing J, Sonntag E, Sticht H, Eichler J, Marschall M. Muller YA, et al. Among authors: hage s. J Biol Chem. 2020 Mar 6;295(10):3189-3201. doi: 10.1074/jbc.RA119.011546. Epub 2020 Jan 24. J Biol Chem. 2020. PMID: 31980459 Free PMC article.

4

Patterns of Autologous and Nonautologous Interactions Between Core Nuclear Egress Complex (NEC) Proteins of α-, β- and γ-Herpesviruses.

Häge S, Sonntag E, Borst EM, Tannig P, Seyler L, Bäuerle T, Bailer SM, Lee CP, Müller R, Wangen C, Milbradt J, Marschall M. Häge S, et al. Viruses. 2020 Mar 11;12(3):303. doi: 10.3390/v12030303. Viruses. 2020. PMID: 32168891 Free PMC article.

5

A quantitative nuclear egress assay to investigate the nucleocytoplasmic capsid release of human cytomegalovirus.

Häge S, Horsch D, Stilp AC, Kicuntod J, Müller R, Hamilton ST, Egilmezer E, Rawlinson WD, Stamminger T, Sonntag E, Marschall M. Häge S, et al. J Virol Methods. 2020 Sep;283:113909. doi: 10.1016/j.jviromet.2020.113909. Epub 2020 Jun 13. J Virol Methods. 2020. PMID: 32544419

6

Nuclear Egress Complexes of HCMV and Other Herpesviruses: Solving the Puzzle of Sequence Coevolution, Conserved Structures and Subfamily-Spanning Binding Properties.

Marschall M, Häge S, Conrad M, Alkhashrom S, Kicuntod J, Schweininger J, Kriegel M, Lösing J, Tillmanns J, Neipel F, Eichler J, Muller YA, Sticht H. Marschall M, et al. Among authors: hage s. Viruses. 2020 Jun 24;12(6):683. doi: 10.3390/v12060683. Viruses. 2020. PMID: 32599939 Free PMC article. Review.

7

IMU-838, a Developmental DHODH Inhibitor in Phase II for Autoimmune Disease, Shows Anti-SARS-CoV-2 and Broad-Spectrum Antiviral Efficacy In Vitro.

Hahn F, Wangen C, Häge S, Peter AS, Dobler G, Hurst B, Julander J, Fuchs J, Ruzsics Z, Überla K, Jäck HM, Ptak R, Muehler A, Gröppel M, Vitt D, Peelen E, Kohlhof H, Marschall M. Hahn F, et al. Among authors: hage s. Viruses. 2020 Dec 5;12(12):1394. doi: 10.3390/v12121394. Viruses. 2020. PMID: 33291455 Free PMC article.

8

Phenotypical Characterization of the Nuclear Egress of Recombinant Cytomegaloviruses Reveals Defective Replication upon ORF-UL50 Deletion but Not pUL50 Phosphosite Mutation.

Häge S, Sonntag E, Svrlanska A, Borst EM, Stilp AC, Horsch D, Müller R, Kropff B, Milbradt J, Stamminger T, Schlötzer-Schrehardt U, Marschall M. Häge S, et al. Viruses. 2021 Jan 22;13(2):165. doi: 10.3390/v13020165. Viruses. 2021. PMID: 33499341 Free PMC article.

9

Properties of Oligomeric Interaction of the Cytomegalovirus Core Nuclear Egress Complex (NEC) and Its Sensitivity to an NEC Inhibitory Small Molecule.

Kicuntod J, Alkhashrom S, Häge S, Diewald B, Müller R, Hahn F, Lischka P, Sticht H, Eichler J, Marschall M. Kicuntod J, et al. Among authors: hage s. Viruses. 2021 Mar 11;13(3):462. doi: 10.3390/v13030462. Viruses. 2021. PMID: 33799898 Free PMC article.

10

Exploring the Human Cytomegalovirus Core Nuclear Egress Complex as a Novel Antiviral Target: A New Type of Small Molecule Inhibitors.

Alkhashrom S, Kicuntod J, Häge S, Schweininger J, Muller YA, Lischka P, Marschall M, Eichler J. Alkhashrom S, et al. Among authors: hage s. Viruses. 2021 Mar 12;13(3):471. doi: 10.3390/v13030471. Viruses. 2021. PMID: 33809234 Free PMC article.

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