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Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome.
Vernia S, Lee A, Kennedy NJ, Han MS, Isasa M, Cavanagh-Kyros J, Roy A, Syed A, Chaudhry S, Edwards YJK, Gygi SP, Gao G, Davis RJ. Vernia S, et al. Among authors: gygi sp. Proc Natl Acad Sci U S A. 2022 Nov;119(44):e2210434119. doi: 10.1073/pnas.2210434119. Epub 2022 Oct 25. Proc Natl Acad Sci U S A. 2022. PMID: 36282921 Free PMC article.
Targeting oncoproteins with a positive selection assay for protein degraders.
Koduri V, Duplaquet L, Lampson BL, Wang AC, Sabet AH, Ishoey M, Paulk J, Teng M, Harris IS, Endress JE, Liu X, Dasilva E, Paulo JA, Briggs KJ, Doench JG, Ott CJ, Zhang T, Donovan KA, Fischer ES, Gygi SP, Gray NS, Bradner J, Medin JA, Buhrlage SJ, Oser MG, Kaelin WG Jr. Koduri V, et al. Among authors: gygi sp. Sci Adv. 2021 Feb 5;7(6):eabd6263. doi: 10.1126/sciadv.abd6263. Print 2021 Feb. Sci Adv. 2021. PMID: 33547076 Free PMC article.
Large-scale characterization of HeLa cell nuclear phosphoproteins.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP. Beausoleil SA, et al. Among authors: gygi sp. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12130-5. doi: 10.1073/pnas.0404720101. Epub 2004 Aug 9. Proc Natl Acad Sci U S A. 2004. PMID: 15302935 Free PMC article.
Large-scale phosphorylation analysis of mouse liver.
Villén J, Beausoleil SA, Gerber SA, Gygi SP. Villén J, et al. Among authors: gygi sp. Proc Natl Acad Sci U S A. 2007 Jan 30;104(5):1488-93. doi: 10.1073/pnas.0609836104. Epub 2007 Jan 22. Proc Natl Acad Sci U S A. 2007. PMID: 17242355 Free PMC article.
A quantitative atlas of mitotic phosphorylation.
Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP. Dephoure N, et al. Among authors: gygi sp. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10762-7. doi: 10.1073/pnas.0805139105. Epub 2008 Jul 31. Proc Natl Acad Sci U S A. 2008. PMID: 18669648 Free PMC article.
698 results