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WNT signaling inducing activity in ascites predicts poor outcome in ovarian cancer.
Theranostics. 2020 Jan 1;10(2):537-552. doi: 10.7150/thno.37423. eCollection 2020.
Theranostics. 2020.
PMID: 31903136
Free PMC article.
The planar cell polarity protein VANG-1/Vangl negatively regulates Wnt/β-catenin signaling through a Dvl dependent mechanism.
Mentink RA, Rella L, Radaszkiewicz TW, Gybel T, Betist MC, Bryja V, Korswagen HC.
Mentink RA, et al. Among authors: gybel t.
PLoS Genet. 2018 Dec 7;14(12):e1007840. doi: 10.1371/journal.pgen.1007840. eCollection 2018 Dec.
PLoS Genet. 2018.
PMID: 30532125
Free PMC article.
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Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1.
Harnoš J, Cañizal MCA, Jurásek M, Kumar J, Holler C, Schambony A, Hanáková K, Bernatík O, Zdráhal Z, Gömöryová K, Gybeľ T, Radaszkiewicz TW, Kravec M, Trantírek L, Ryneš J, Dave Z, Fernández-Llamazares AI, Vácha R, Tripsianes K, Hoffmann C, Bryja V.
Harnoš J, et al. Among authors: gybel t.
Nat Commun. 2019 Apr 18;10(1):1804. doi: 10.1038/s41467-019-09651-7.
Nat Commun. 2019.
PMID: 31000703
Free PMC article.
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RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.
Radaszkiewicz T, Nosková M, Gömöryová K, Vondálová Blanářová O, Radaszkiewicz KA, Picková M, Víchová R, Gybeľ T, Kaiser K, Demková L, Kučerová L, Bárta T, Potěšil D, Zdráhal Z, Souček K, Bryja V.
Radaszkiewicz T, et al. Among authors: gybel t.
Elife. 2021 Oct 27;10:e65759. doi: 10.7554/eLife.65759.
Elife. 2021.
PMID: 34702444
Free PMC article.
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Dual specificity phosphatase 7 drives the formation of cardiac mesoderm in mouse embryonic stem cells.
Sladeček S, Radaszkiewicz KA, Bőhmová M, Gybeľ T, Radaszkiewicz TW, Pacherník J.
Sladeček S, et al. Among authors: gybel t.
PLoS One. 2022 Oct 13;17(10):e0275860. doi: 10.1371/journal.pone.0275860. eCollection 2022.
PLoS One. 2022.
PMID: 36227898
Free PMC article.
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Dishevelled enables casein kinase 1-mediated phosphorylation of Frizzled 6 required for cell membrane localization.
Strakova K, Kowalski-Jahn M, Gybel T, Valnohova J, Dhople VM, Harnos J, Bernatik O, Ganji RS, Zdrahal Z, Mulder J, Lindskog C, Bryja V, Schulte G.
Strakova K, et al. Among authors: gybel t.
J Biol Chem. 2018 Nov 30;293(48):18477-18493. doi: 10.1074/jbc.RA118.004656. Epub 2018 Oct 11.
J Biol Chem. 2018.
PMID: 30309985
Free PMC article.
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Discovery of Potent and Exquisitely Selective Inhibitors of Kinase CK1 with Tunable Isoform Selectivity.
Němec V, Khirsariya P, Janovská P, Moyano PM, Maier L, Procházková P, Kebková P, Gybel' T, Berger BT, Chaikuad A, Reinecke M, Kuster B, Knapp S, Bryja V, Paruch K.
Němec V, et al. Among authors: gybel t.
Angew Chem Int Ed Engl. 2023 Mar 6;62(11):e202217532. doi: 10.1002/anie.202217532. Epub 2023 Feb 2.
Angew Chem Int Ed Engl. 2023.
PMID: 36625768
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