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GTP signaling links metabolism, DNA repair, and responses to genotoxic stress.
Zhou W, Zhao Z, Lin A, Yang J, Xu J, Kari WR, Yang A, Li J, Solanki S, Speth J, Walker N, Scott AJ, Kothari AU, Yao Y, Peterson ER, Korimerla N, Werner CK, Liang J, Jacobson J, Palavalasa S, Obrien AM, Elaimy AL, Ferris SP, Zhao SG, Sarkaria JN, Győrffy B, Zhang S, Al-Holou WN, Umemura Y, Morgan MA, Lawrence TS, Lyssiotis CA, Peters-Golden M, Shah YM, Wahl DR. Zhou W, et al. Among authors: gyorffy b. bioRxiv [Preprint]. 2023 Apr 13:2023.04.12.536297. doi: 10.1101/2023.04.12.536297. bioRxiv. 2023. PMID: 37090571 Free PMC article. Updated. Preprint.
Identifying Ferroptosis Inducers, HDAC, and RTK Inhibitor Sensitivity in Melanoma Subtypes through Unbiased Drug Target Prediction.
Pla I, Szabolcs BL, Péter PN, Ujfaludi Z, Kim Y, Horvatovich P, Sanchez A, Pawlowski K, Wieslander E, Guedes J, Pál DM, Ascsillán AA, Betancourt LH, Németh IB, Gil J, de Almeida NP, Szeitz B, Szadai L, Doma V, Woldmar N, Bartha Á, Pahi Z, Pankotai T, Győrffy B, Szasz AM, Domont G, Nogueira F, Kwon HJ, Appelqvist R, Kárpáti S, Fenyö D, Malm J, Marko-Varga G, Kemény LV. Pla I, et al. Among authors: gyorffy b. bioRxiv [Preprint]. 2024 Feb 12:2024.02.08.579424. doi: 10.1101/2024.02.08.579424. bioRxiv. 2024. PMID: 38545623 Free PMC article. Preprint.
Transient loss of Polycomb components induces an epigenetic cancer fate.
Parreno V, Loubiere V, Schuettengruber B, Fritsch L, Rawal CC, Erokhin M, Győrffy B, Normanno D, Di Stefano M, Moreaux J, Butova NL, Chiolo I, Chetverina D, Martinez AM, Cavalli G. Parreno V, et al. Among authors: gyorffy b. Nature. 2024 Apr 24. doi: 10.1038/s41586-024-07328-w. Online ahead of print. Nature. 2024. PMID: 38658752
Mediator kinase inhibition reverses castration resistance of advanced prostate cancer.
Li J, Hilimire TA, Yueying L, Wang L, Liang J, Győrffy B, Sikirzhytski V, Ji H, Zhang L, Cheng C, Ding X, Kerr KR, Dowling CE, Chumanevich AA, Mack ZT, Schools GP, Lim CU, Ellis L, Zi X, Porter DC, Broude EV, McInnes C, Wilding G, Lilly MB, Roninson IB, Chen M. Li J, et al. Among authors: gyorffy b. J Clin Invest. 2024 Mar 28:e176709. doi: 10.1172/JCI176709. Online ahead of print. J Clin Invest. 2024. PMID: 38546787 Free article.
Long-term Multimodal Recording Reveals Epigenetic Adaptation Routes in Dormant Breast Cancer Cells.
Rosano D, Sofyali E, Dhiman H, Ghirardi C, Ivanoiu D, Heide T, Vingiani A, Bertolotti A, Pruneri G, Canale E, Dewhurst HF, Saha D, Slaven N, Barozzi I, Li T, Zemlyanskiy G, Phillips H, James C, Győrffy B, Lynn C, Cresswell GD, Rehman F, Noberini R, Bonaldi T, Sottoriva A, Magnani L. Rosano D, et al. Among authors: gyorffy b. Cancer Discov. 2024 May 1;14(5):866-889. doi: 10.1158/2159-8290.CD-23-1161. Cancer Discov. 2024. PMID: 38527495 Free PMC article.
Genomic and Immunologic Correlates in Prostate Cancer with High Expression of KLK2.
Paniagua-Herranz L, Moreno I, Nieto-Jiménez C, Garcia-Lorenzo E, Díaz-Tejeiro C, Sanvicente A, Doger B, Pedregal M, Ramón J, Bartolomé J, Manzano A, Gyorffy B, Gutierrez-Uzquiza Á, Pérez Segura P, Calvo E, Moreno V, Ocana A. Paniagua-Herranz L, et al. Among authors: gyorffy b. Int J Mol Sci. 2024 Feb 13;25(4):2222. doi: 10.3390/ijms25042222. Int J Mol Sci. 2024. PMID: 38396898 Free PMC article.
435 results