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VEGF-targeted therapy stably modulates the glycolytic phenotype of tumor cells.
Curtarello M, Zulato E, Nardo G, Valtorta S, Guzzo G, Rossi E, Esposito G, Msaki A, Pastò A, Rasola A, Persano L, Ciccarese F, Bertorelle R, Todde S, Plebani M, Schroer H, Walenta S, Mueller-Klieser W, Amadori A, Moresco RM, Indraccolo S. Curtarello M, et al. Among authors: guzzo g. Cancer Res. 2015 Jan 1;75(1):120-33. doi: 10.1158/0008-5472.CAN-13-2037. Epub 2014 Nov 7. Cancer Res. 2015. PMID: 25381153
Absence of Neurofibromin Induces an Oncogenic Metabolic Switch via Mitochondrial ERK-Mediated Phosphorylation of the Chaperone TRAP1.
Masgras I, Ciscato F, Brunati AM, Tibaldi E, Indraccolo S, Curtarello M, Chiara F, Cannino G, Papaleo E, Lambrughi M, Guzzo G, Gambalunga A, Pizzi M, Guzzardo V, Rugge M, Vuljan SE, Calabrese F, Bernardi P, Rasola A. Masgras I, et al. Among authors: guzzo g. Cell Rep. 2017 Jan 17;18(3):659-672. doi: 10.1016/j.celrep.2016.12.056. Cell Rep. 2017. PMID: 28099845 Free article.
Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis.
Kowalik MA, Guzzo G, Morandi A, Perra A, Menegon S, Masgras I, Trevisan E, Angioni MM, Fornari F, Quagliata L, Ledda-Columbano GM, Gramantieri L, Terracciano L, Giordano S, Chiarugi P, Rasola A, Columbano A. Kowalik MA, et al. Among authors: guzzo g. Oncotarget. 2016 May 31;7(22):32375-93. doi: 10.18632/oncotarget.8632. Oncotarget. 2016. PMID: 27070090 Free PMC article.
Aerobic glycolysis tunes YAP/TAZ transcriptional activity.
Enzo E, Santinon G, Pocaterra A, Aragona M, Bresolin S, Forcato M, Grifoni D, Pession A, Zanconato F, Guzzo G, Bicciato S, Dupont S. Enzo E, et al. Among authors: guzzo g. EMBO J. 2015 May 12;34(10):1349-70. doi: 10.15252/embj.201490379. Epub 2015 Mar 21. EMBO J. 2015. PMID: 25796446 Free PMC article.
70 results