Guzmán EA - Search Results

1

Dragmacidin G, a Bioactive Bis-Indole Alkaloid from a Deep-Water Sponge of the Genus Spongosorites.

Wright AE, Killday KB, Chakrabarti D, Guzmán EA, Harmody D, McCarthy PJ, Pitts T, Pomponi SA, Reed JK, Roberts BF, Rodrigues Felix C, Rohde KH. Wright AE, et al. Among authors: guzman ea. Mar Drugs. 2017 Jan 11;15(1):16. doi: 10.3390/md15010016. Mar Drugs. 2017. PMID: 28085024 Free PMC article.

2

Neopeltolide, a macrolide from a lithistid sponge of the family Neopeltidae.

Wright AE, Botelho JC, Guzmán E, Harmody D, Linley P, McCarthy PJ, Pitts TP, Pomponi SA, Reed JK. Wright AE, et al. J Nat Prod. 2007 Mar;70(3):412-6. doi: 10.1021/np060597h. Epub 2007 Feb 20. J Nat Prod. 2007. PMID: 17309301

3

Total synthesis and biological evaluation of potent analogues of dictyostatin: modification of the C2-C6 dienoate region.

Paterson I, Gardner NM, Guzmán E, Wright AE. Paterson I, et al. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6268-72. doi: 10.1016/j.bmcl.2008.09.109. Epub 2008 Oct 11. Bioorg Med Chem Lett. 2008. PMID: 18951787

4

Total synthesis and biological evaluation of novel C2-C6 region analogues of dictyostatin.

Paterson I, Gardner NM, Guzmán E, Wright AE. Paterson I, et al. Bioorg Med Chem. 2009 Mar 15;17(6):2282-9. doi: 10.1016/j.bmc.2008.10.084. Epub 2008 Nov 5. Bioorg Med Chem. 2009. PMID: 19022679

5

Selective cytotoxic activity of the marine-derived batzelline compounds against pancreatic cancer cell lines.

Guzmán EA, Johnson JD, Carrier MK, Meyer CI, Pitts TP, Gunasekera SP, Wright AE. Guzmán EA, et al. Anticancer Drugs. 2009 Feb;20(2):149-55. doi: 10.1097/CAD.0b013e32831fa39e. Anticancer Drugs. 2009. PMID: 19209032 Free PMC article.

6

Isolation, synthesis, and biological activity of aphrocallistin, an adenine-substituted bromotyramine metabolite from the Hexactinellida sponge Aphrocallistes beatrix.

Wright AE, Roth GP, Hoffman JK, Divlianska DB, Pechter D, Sennett SH, Guzmán EA, Linley P, McCarthy PJ, Pitts TP, Pomponi SA, Reed JK. Wright AE, et al. Among authors: guzman ea. J Nat Prod. 2009 Jun;72(6):1178-83. doi: 10.1021/np900183v. J Nat Prod. 2009. PMID: 19459694 Free PMC article.

7

Early effects of lasonolide a on pancreatic cancer cells.

Isbrucker RA, Guzmán EA, Pitts TP, Wright AE. Isbrucker RA, et al. Among authors: guzman ea. J Pharmacol Exp Ther. 2009 Nov;331(2):733-9. doi: 10.1124/jpet.109.155531. Epub 2009 Aug 19. J Pharmacol Exp Ther. 2009. PMID: 19692635 Free PMC article.

8

Total synthesis of a library of designed hybrids of the microtubule-stabilising anticancer agents taxol, discodermolide and dictyostatin.

Paterson I, Naylor GJ, Fujita T, Guzmán E, Wright AE. Paterson I, et al. Chem Commun (Camb). 2010 Jan 14;46(2):261-3. doi: 10.1039/b921237j. Epub 2009 Nov 24. Chem Commun (Camb). 2010. PMID: 20024345

9

A novel activity from an old compound: Manzamine A reduces the metastatic potential of AsPC-1 pancreatic cancer cells and sensitizes them to TRAIL-induced apoptosis.

Guzmán EA, Johnson JD, Linley PA, Gunasekera SE, Wright AE. Guzmán EA, et al. Invest New Drugs. 2011 Oct;29(5):777-85. doi: 10.1007/s10637-010-9422-6. Epub 2010 Mar 30. Invest New Drugs. 2011. PMID: 20352293 Free PMC article.

10

Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol.

Paterson I, Naylor GJ, Gardner NM, Guzmán E, Wright AE. Paterson I, et al. Chem Asian J. 2011 Feb 1;6(2):459-73. doi: 10.1002/asia.201000541. Epub 2010 Oct 28. Chem Asian J. 2011. PMID: 21254424 Free PMC article.

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