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E1a is an exogenous in vivo tumour suppressor.
Cimas FJ, Callejas-Valera JL, García-Olmo DC, Hernández-Losa J, Melgar-Rojas P, Ruiz-Hidalgo MJ, Pascual-Serra R, Ortega-Muelas M, Roche O, Marcos P, Garcia-Gil E, Fernandez-Aroca DM, Ramón Y Cajal S, Gutkind JS, Sanchez-Prieto R. Cimas FJ, et al. Among authors: gutkind js. Cancer Lett. 2017 Jul 28;399:74-81. doi: 10.1016/j.canlet.2017.04.010. Epub 2017 Apr 15. Cancer Lett. 2017. PMID: 28416454
HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers.
Ren S, Gaykalova DA, Guo T, Favorov AV, Fertig EJ, Tamayo P, Callejas-Valera JL, Allevato M, Gilardi M, Santos J, Fukusumi T, Sakai A, Ando M, Sadat S, Liu C, Xu G, Fisch KM, Wang Z, Molinolo AA, Gutkind JS, Ideker T, Koch WM, Califano JA. Ren S, et al. Among authors: gutkind js. Oncogene. 2020 Oct;39(40):6327-6339. doi: 10.1038/s41388-020-01431-8. Epub 2020 Aug 26. Oncogene. 2020. PMID: 32848210 Free PMC article.
The anti-tumour activity of DNA methylation inhibitor 5-aza-2'-deoxycytidine is enhanced by the common analgesic paracetamol through induction of oxidative stress.
Gleneadie HJ, Baker AH, Batis N, Bryant J, Jiang Y, Clokie SJH, Mehanna H, Garcia P, Gendoo DMA, Roberts S, Burley M, Molinolo AA, Gutkind JS, Scheven BA, Cooper PR, Parish JL, Khanim FL, Wiench M. Gleneadie HJ, et al. Among authors: gutkind js. Cancer Lett. 2021 Mar 31;501:172-186. doi: 10.1016/j.canlet.2020.12.029. Epub 2021 Jan 5. Cancer Lett. 2021. PMID: 33359448 Free PMC article.
532 results