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Second-generation 4,5,6,7-tetrahydrobenzo[d]thiazoles as novel DNA gyrase inhibitors.
Lamut A, Skok Ž, Barančoková M, Gutierrez LJ, Cruz CD, Tammela P, Draskovits G, Szili PÉ, Nyerges Á, Pál C, Molek P, Bratkovič T, Ilaš J, Zidar N, Zega A, Enriz RD, Kikelj D, Tomašič T. Lamut A, et al. Among authors: gutierrez lj. Future Med Chem. 2020 Feb;12(4):277-297. doi: 10.4155/fmc-2019-0127. Epub 2020 Feb 11. Future Med Chem. 2020. PMID: 32043377
The nitrone spin trap 5,5‑dimethyl‑1‑pyrroline N‑oxide binds to toll-like receptor-2-TIR-BB-loop domain and dampens downstream inflammatory signaling.
Muñoz MD, Gutierrez LJ, Delignat S, Russick J, Gomez Mejiba SE, Lacroix-Desmazes S, Enriz RD, Ramirez DC. Muñoz MD, et al. Among authors: gutierrez lj. Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1152-1159. doi: 10.1016/j.bbadis.2019.01.005. Epub 2019 Jan 23. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 30684639 Free article.
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