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Page 1
Loss of endothelial CFTR drives barrier failure and edema formation in lung infection and can be targeted by CFTR potentiation.
Erfinanda L, Zou L, Gutbier B, Kneller L, Weidenfeld S, Michalick L, Lei D, Reppe K, Teixeira Alves LG, Schneider B, Zhang Q, Li C, Fatykhova D, Schneider P, Liedtke W, Sohara E, Mitchell TJ, Gruber AD, Hocke A, Hippenstiel S, Suttorp N, Olschewski A, Mall MA, Witzenrath M, Kuebler WM. Erfinanda L, et al. Among authors: gutbier b. Sci Transl Med. 2022 Dec 7;14(674):eabg8577. doi: 10.1126/scitranslmed.abg8577. Epub 2022 Dec 7. Sci Transl Med. 2022. PMID: 36475904
Role of platelet-activating factor in pneumolysin-induced acute lung injury.
Witzenrath M, Gutbier B, Owen JS, Schmeck B, Mitchell TJ, Mayer K, Thomas MJ, Ishii S, Rosseau S, Suttorp N, Schütte H. Witzenrath M, et al. Among authors: gutbier b. Crit Care Med. 2007 Jul;35(7):1756-62. doi: 10.1097/01.CCM.0000269212.84709.23. Crit Care Med. 2007. PMID: 17522574
Systemic use of the endolysin Cpl-1 rescues mice with fatal pneumococcal pneumonia.
Witzenrath M, Schmeck B, Doehn JM, Tschernig T, Zahlten J, Loeffler JM, Zemlin M, Müller H, Gutbier B, Schütte H, Hippenstiel S, Fischetti VA, Suttorp N, Rosseau S. Witzenrath M, et al. Among authors: gutbier b. Crit Care Med. 2009 Feb;37(2):642-9. doi: 10.1097/CCM.0b013e31819586a6. Crit Care Med. 2009. PMID: 19114881
Simvastatin attenuates ventilator-induced lung injury in mice.
Müller HC, Hellwig K, Rosseau S, Tschernig T, Schmiedl A, Gutbier B, Schmeck B, Hippenstiel S, Peters H, Morawietz L, Suttorp N, Witzenrath M. Müller HC, et al. Among authors: gutbier b. Crit Care. 2010;14(4):R143. doi: 10.1186/cc9209. Epub 2010 Jul 30. Crit Care. 2010. PMID: 20673352 Free PMC article.
Adrenomedullin attenuates ventilator-induced lung injury in mice.
Müller HC, Witzenrath M, Tschernig T, Gutbier B, Hippenstiel S, Santel A, Suttorp N, Rosseau S. Müller HC, et al. Among authors: gutbier b. Thorax. 2010 Dec;65(12):1077-84. doi: 10.1136/thx.2010.135996. Epub 2010 Oct 22. Thorax. 2010. PMID: 20971983
The Sphingosine-1 Phosphate receptor agonist FTY720 dose dependently affected endothelial integrity in vitro and aggravated ventilator-induced lung injury in mice.
Müller HC, Hocke AC, Hellwig K, Gutbier B, Peters H, Schönrock SM, Tschernig T, Schmiedl A, Hippenstiel S, N'Guessan PD, Rosseau S, Suttorp N, Witzenrath M. Müller HC, et al. Among authors: gutbier b. Pulm Pharmacol Ther. 2011 Aug;24(4):377-85. doi: 10.1016/j.pupt.2011.01.017. Epub 2011 Mar 23. Pulm Pharmacol Ther. 2011. PMID: 21419858
37 results