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Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain.
Bogie JFJ, Grajchen E, Wouters E, Corrales AG, Dierckx T, Vanherle S, Mailleux J, Gervois P, Wolfs E, Dehairs J, Van Broeckhoven J, Bowman AP, Lambrichts I, Gustafsson JÅ, Remaley AT, Mulder M, Swinnen JV, Haidar M, Ellis SR, Ntambi JM, Zelcer N, Hendriks JJA. Bogie JFJ, et al. Among authors: gustafsson ja. J Exp Med. 2020 May 4;217(5):e20191660. doi: 10.1084/jem.20191660. J Exp Med. 2020. PMID: 32097464 Free PMC article.
Liver X Receptor Alpha Is Important in Maintaining Blood-Brain Barrier Function.
Wouters E, de Wit NM, Vanmol J, van der Pol SMA, van Het Hof B, Sommer D, Loix M, Geerts D, Gustafsson JA, Steffensen KR, Vanmierlo T, Bogie JFJ, Hendriks JJA, de Vries HE. Wouters E, et al. Among authors: gustafsson ja. Front Immunol. 2019 Jul 31;10:1811. doi: 10.3389/fimmu.2019.01811. eCollection 2019. Front Immunol. 2019. PMID: 31417573 Free PMC article.
Myelin-derived lipids modulate macrophage activity by liver X receptor activation.
Bogie JF, Timmermans S, Huynh-Thu VA, Irrthum A, Smeets HJ, Gustafsson JÅ, Steffensen KR, Mulder M, Stinissen P, Hellings N, Hendriks JJ. Bogie JF, et al. Among authors: gustafsson ja. PLoS One. 2012;7(9):e44998. doi: 10.1371/journal.pone.0044998. Epub 2012 Sep 12. PLoS One. 2012. PMID: 22984598 Free PMC article.
Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis.
Endo-Umeda K, Kim E, Thomas DG, Liu W, Dou H, Yalcinkaya M, Abramowicz S, Xiao T, Antonson P, Gustafsson JÅ, Makishima M, Reilly MP, Wang N, Tall AR. Endo-Umeda K, et al. Among authors: gustafsson ja. Arterioscler Thromb Vasc Biol. 2022 Jun;42(6):719-731. doi: 10.1161/ATVBAHA.122.317583. Epub 2022 Apr 28. Arterioscler Thromb Vasc Biol. 2022. PMID: 35477277 Free PMC article.
Liver X receptors are required for thymic resilience and T cell output.
Chan CT, Fenn AM, Harder NK, Mindur JE, McAlpine CS, Patel J, Valet C, Rattik S, Iwamoto Y, He S, Anzai A, Kahles F, Poller WC, Janssen H, Wong LP, Fernandez-Hernando C, Koolbergen DR, van der Laan AM, Yvan-Charvet L, Sadreyev RI, Nahrendorf M, Westerterp M, Tall AR, Gustafsson JA, Swirski FK. Chan CT, et al. Among authors: gustafsson ja. J Exp Med. 2020 Oct 5;217(10):e20200318. doi: 10.1084/jem.20200318. J Exp Med. 2020. PMID: 32716519 Free PMC article.
The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils.
Raccosta L, Fontana R, Maggioni D, Lanterna C, Villablanca EJ, Paniccia A, Musumeci A, Chiricozzi E, Trincavelli ML, Daniele S, Martini C, Gustafsson JA, Doglioni C, Feo SG, Leiva A, Ciampa MG, Mauri L, Sensi C, Prinetti A, Eberini I, Mora JR, Bordignon C, Steffensen KR, Sonnino S, Sozzani S, Traversari C, Russo V. Raccosta L, et al. Among authors: gustafsson ja. J Exp Med. 2013 Aug 26;210(9):1711-28. doi: 10.1084/jem.20130440. Epub 2013 Jul 29. J Exp Med. 2013. PMID: 23897983 Free PMC article.
1,474 results