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DNMT3A Harboring Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks.
Venugopal K, Feng Y, Nowialis P, Xu H, Shabashvili DE, Berntsen CM, Kaur P, Krajcik KI, Taragjini C, Zaroogian Z, Casellas Román HL, Posada LM, Gunaratne C, Li J, Dupéré-Richer D, Bennett RL, Pondugula S, Riva A, Cogle CR, Opavsky R, Law BK, Bhaduri-McIntosh S, Kubicek S, Staber PB, Licht JD, Bird JE, Guryanova OA. Venugopal K, et al. Among authors: guryanova oa. Clin Cancer Res. 2022 Feb 15;28(4):756-769. doi: 10.1158/1078-0432.CCR-21-2863. Clin Cancer Res. 2022. PMID: 34716195 Free PMC article.
DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling.
Guryanova OA, Shank K, Spitzer B, Luciani L, Koche RP, Garrett-Bakelman FE, Ganzel C, Durham BH, Mohanty A, Hoermann G, Rivera SA, Chramiec AG, Pronier E, Bastian L, Keller MD, Tovbin D, Loizou E, Weinstein AR, Gonzalez AR, Lieu YK, Rowe JM, Pastore F, McKenney AS, Krivtsov AV, Sperr WR, Cross JR, Mason CE, Tallman MS, Arcila ME, Abdel-Wahab O, Armstrong SA, Kubicek S, Staber PB, Gönen M, Paietta EM, Melnick AM, Nimer SD, Mukherjee S, Levine RL. Guryanova OA, et al. Nat Med. 2016 Dec;22(12):1488-1495. doi: 10.1038/nm.4210. Epub 2016 Nov 14. Nat Med. 2016. PMID: 27841873 Free PMC article.
FQI1: a transcription-methylation switch for cancer.
Guryanova OA, Licht JD. Guryanova OA, et al. Oncotarget. 2017 Feb 21;8(8):12536-12537. doi: 10.18632/oncotarget.15087. Oncotarget. 2017. PMID: 28177910 Free PMC article. No abstract available.
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers.
Glass JL, Hassane D, Wouters BJ, Kunimoto H, Avellino R, Garrett-Bakelman FE, Guryanova OA, Bowman R, Redlich S, Intlekofer AM, Meydan C, Qin T, Fall M, Alonso A, Guzman ML, Valk PJM, Thompson CB, Levine R, Elemento O, Delwel R, Melnick A, Figueroa ME. Glass JL, et al. Among authors: guryanova oa. Cancer Discov. 2017 Aug;7(8):868-883. doi: 10.1158/2159-8290.CD-16-1032. Epub 2017 Apr 13. Cancer Discov. 2017. PMID: 28408400 Free PMC article.
Alterations to DNMT3A in Hematologic Malignancies.
Venugopal K, Feng Y, Shabashvili D, Guryanova OA. Venugopal K, et al. Among authors: guryanova oa. Cancer Res. 2021 Jan 15;81(2):254-263. doi: 10.1158/0008-5472.CAN-20-3033. Epub 2020 Oct 21. Cancer Res. 2021. PMID: 33087320 Free PMC article. Review.
[No title available]
[No authors listed] [No authors listed] PMID: 33293526
42 results