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The 3D Genome as a Target for Anticancer Therapy.
Kantidze OL, Gurova KV, Studitsky VM, Razin SV. Kantidze OL, et al. Among authors: gurova kv. Trends Mol Med. 2020 Feb;26(2):141-149. doi: 10.1016/j.molmed.2019.09.011. Epub 2019 Oct 31. Trends Mol Med. 2020. PMID: 31679987 Free PMC article. Review.
Structure and function of the histone chaperone FACT - Resolving FACTual issues.
Gurova K, Chang HW, Valieva ME, Sandlesh P, Studitsky VM. Gurova K, et al. Biochim Biophys Acta Gene Regul Mech. 2018 Jul 25:S1874-9399(18)30159-7. doi: 10.1016/j.bbagrm.2018.07.008. Online ahead of print. Biochim Biophys Acta Gene Regul Mech. 2018. PMID: 30055319 Free PMC article. Review.
Mechanism of FACT removal from transcribed genes by anticancer drugs curaxins.
Chang HW, Valieva ME, Safina A, Chereji RV, Wang J, Kulaeva OI, Morozov AV, Kirpichnikov MP, Feofanov AV, Gurova KV, Studitsky VM. Chang HW, et al. Among authors: gurova kv. Sci Adv. 2018 Nov 7;4(11):eaav2131. doi: 10.1126/sciadv.aav2131. eCollection 2018 Nov. Sci Adv. 2018. PMID: 30417101 Free PMC article.
The anti-cancer drugs curaxins target spatial genome organization.
Kantidze OL, Luzhin AV, Nizovtseva EV, Safina A, Valieva ME, Golov AK, Velichko AK, Lyubitelev AV, Feofanov AV, Gurova KV, Studitsky VM, Razin SV. Kantidze OL, et al. Among authors: gurova kv. Nat Commun. 2019 Mar 29;10(1):1441. doi: 10.1038/s41467-019-09500-7. Nat Commun. 2019. PMID: 30926878 Free PMC article.
Comparison of cell response to chromatin and DNA damage.
Luzhin A, Rajan P, Safina A, Leonova K, Stablewski A, Wang J, Robinson D, Isaeva N, Kantidze O, Gurova K. Luzhin A, et al. Nucleic Acids Res. 2023 Nov 27;51(21):11836-11855. doi: 10.1093/nar/gkad865. Nucleic Acids Res. 2023. PMID: 37855682 Free PMC article.
Facilitates chromatin transcription complex is an "accelerator" of tumor transformation and potential marker and target of aggressive cancers.
Garcia H, Miecznikowski JC, Safina A, Commane M, Ruusulehto A, Kilpinen S, Leach RW, Attwood K, Li Y, Degan S, Omilian AR, Guryanova O, Papantonopoulou O, Wang J, Buck M, Liu S, Morrison C, Gurova KV. Garcia H, et al. Among authors: gurova kv. Cell Rep. 2013 Jul 11;4(1):159-73. doi: 10.1016/j.celrep.2013.06.013. Epub 2013 Jul 3. Cell Rep. 2013. PMID: 23831030 Free PMC article.
71 results