Gurgul-Convey E - Search Results

1

Sphingosine-1 Phosphate Lyase Regulates Sensitivity of Pancreatic Beta-Cells to Lipotoxicity.

Tang Y, Plötz T, Gräler MH, Gurgul-Convey E. Tang Y, et al. Among authors: gurgul convey e. Int J Mol Sci. 2021 Oct 8;22(19):10893. doi: 10.3390/ijms221910893. Int J Mol Sci. 2021. PMID: 34639233 Free PMC article.

2

Cytokine toxicity in insulin-producing cells is mediated by nitro-oxidative stress-induced hydroxyl radical formation in mitochondria.

Gurgul-Convey E, Mehmeti I, Lortz S, Lenzen S. Gurgul-Convey E, et al. J Mol Med (Berl). 2011 Aug;89(8):785-98. doi: 10.1007/s00109-011-0747-1. Epub 2011 Apr 13. J Mol Med (Berl). 2011. PMID: 21487676

3

Induction of the intrinsic apoptosis pathway in insulin-secreting cells is dependent on oxidative damage of mitochondria but independent of caspase-12 activation.

Mehmeti I, Gurgul-Convey E, Lenzen S, Lortz S. Mehmeti I, et al. Biochim Biophys Acta. 2011 Oct;1813(10):1827-35. doi: 10.1016/j.bbamcr.2011.06.022. Epub 2011 Jul 8. Biochim Biophys Acta. 2011. PMID: 21784110 Free article.

4

Unveiling a common mechanism of apoptosis in β-cells and neurons in Friedreich's ataxia.

Igoillo-Esteve M, Gurgul-Convey E, Hu A, Romagueira Bichara Dos Santos L, Abdulkarim B, Chintawar S, Marselli L, Marchetti P, Jonas JC, Eizirik DL, Pandolfo M, Cnop M. Igoillo-Esteve M, et al. Hum Mol Genet. 2015 Apr 15;24(8):2274-86. doi: 10.1093/hmg/ddu745. Epub 2014 Dec 30. Hum Mol Genet. 2015. PMID: 25552656

5

Sensitivity profile of the human EndoC-βH1 beta cell line to proinflammatory cytokines.

Gurgul-Convey E, Mehmeti I, Plötz T, Jörns A, Lenzen S. Gurgul-Convey E, et al. Diabetologia. 2016 Oct;59(10):2125-33. doi: 10.1007/s00125-016-4060-y. Epub 2016 Jul 27. Diabetologia. 2016. PMID: 27460666

6

Overexpression of sphingosine-1-phosphate lyase protects insulin-secreting cells against cytokine toxicity.

Hahn C, Tyka K, Saba JD, Lenzen S, Gurgul-Convey E. Hahn C, et al. Among authors: gurgul convey e. J Biol Chem. 2017 Dec 8;292(49):20292-20304. doi: 10.1074/jbc.M117.814491. Epub 2017 Oct 25. J Biol Chem. 2017. PMID: 29070677 Free PMC article.

7

MCPIP1 regulates the sensitivity of pancreatic beta-cells to cytokine toxicity.

Tyka K, Jörns A, Turatsinze JV, Eizirik DL, Lenzen S, Gurgul-Convey E. Tyka K, et al. Among authors: gurgul convey e. Cell Death Dis. 2019 Jan 10;10(1):29. doi: 10.1038/s41419-018-1268-4. Cell Death Dis. 2019. PMID: 30631045 Free PMC article.

8

Sphingolipids in Type 1 Diabetes: Focus on Beta-Cells.

Gurgul-Convey E. Gurgul-Convey E. Cells. 2020 Aug 4;9(8):1835. doi: 10.3390/cells9081835. Cells. 2020. PMID: 32759843 Free PMC article. Review.

9

MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity.

Tyka K, Jörns A, Dunst A, Tang Y, Bryde TH, Mehmeti I, Walentinsson A, Marselli L, Cnop M, Tyrberg B, Marzec MT, Gurgul-Convey E. Tyka K, et al. Among authors: gurgul convey e. Biochim Biophys Acta Mol Basis Dis. 2021 Oct 1;1867(10):166199. doi: 10.1016/j.bbadis.2021.166199. Epub 2021 Jun 16. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 34144091 Free article.

10

Proinflammatory cytokines induce rapid, NO-independent apoptosis, expression of chemotactic mediators and interleukin-32 secretion in human pluripotent stem cell-derived beta cells.

Dettmer R, Niwolik I, Cirksena K, Yoshimoto T, Tang Y, Mehmeti I, Gurgul-Convey E, Naujok O. Dettmer R, et al. Among authors: gurgul convey e. Diabetologia. 2022 May;65(5):829-843. doi: 10.1007/s00125-022-05654-0. Epub 2022 Feb 5. Diabetologia. 2022. PMID: 35122482 Free PMC article.

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