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GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision.
Asher WB, Terry DS, Gregorio GGA, Kahsai AW, Borgia A, Xie B, Modak A, Zhu Y, Jang W, Govindaraju A, Huang LY, Inoue A, Lambert NA, Gurevich VV, Shi L, Lefkowitz RJ, Blanchard SC, Javitch JA. Asher WB, et al. Among authors: gurevich vv. Cell. 2022 May 12;185(10):1661-1675.e16. doi: 10.1016/j.cell.2022.03.042. Epub 2022 Apr 27. Cell. 2022. PMID: 35483373 Free PMC article.
The molecular acrobatics of arrestin activation.
Gurevich VV, Gurevich EV. Gurevich VV, et al. Among authors: gurevich ev. Trends Pharmacol Sci. 2004 Feb;25(2):105-11. doi: 10.1016/j.tips.2003.12.008. Trends Pharmacol Sci. 2004. PMID: 15102497 Review.
Each rhodopsin molecule binds its own arrestin.
Hanson SM, Gurevich EV, Vishnivetskiy SA, Ahmed MR, Song X, Gurevich VV. Hanson SM, et al. Among authors: gurevich vv, gurevich ev. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3125-8. doi: 10.1073/pnas.0610886104. Epub 2007 Feb 20. Proc Natl Acad Sci U S A. 2007. PMID: 17360618 Free PMC article.
269 results