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Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH.
Serpillon S, Floyd BC, Gupte RS, George S, Kozicky M, Neito V, Recchia F, Stanley W, Wolin MS, Gupte SA. Serpillon S, et al. Among authors: gupte sa, gupte rs. Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H153-62. doi: 10.1152/ajpheart.01142.2008. Epub 2009 May 8. Am J Physiol Heart Circ Physiol. 2009. PMID: 19429815 Free PMC article.
Vascular smooth muscle cell contractile protein expression is increased through protein kinase G-dependent and -independent pathways by glucose-6-phosphate dehydrogenase inhibition and deficiency.
Chettimada S, Joshi SR, Dhagia V, Aiezza A 2nd, Lincoln TM, Gupte R, Miano JM, Gupte SA. Chettimada S, et al. Among authors: gupte sa, gupte r. Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H904-H912. doi: 10.1152/ajpheart.00335.2016. Epub 2016 Aug 12. Am J Physiol Heart Circ Physiol. 2016. PMID: 27521420 Free PMC article.
Pluripotent hematopoietic stem cells augment α-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension.
Hashimoto R, Lanier GM, Dhagia V, Joshi SR, Jordan A, Waddell I, Tuder R, Stenmark KR, Wolin MS, McMurtry IF, Gupte SA. Hashimoto R, et al. Among authors: gupte sa. Am J Physiol Lung Cell Mol Physiol. 2020 Feb 1;318(2):L386-L401. doi: 10.1152/ajplung.00327.2019. Epub 2020 Jan 8. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 31913656 Free PMC article.
Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation.
Joshi SR, Kitagawa A, Jacob C, Hashimoto R, Dhagia V, Ramesh A, Zheng C, Zhang H, Jordan A, Waddell I, Leopold J, Hu CJ, McMurtry IF, D'Alessandro A, Stenmark KR, Gupte SA. Joshi SR, et al. Among authors: gupte sa. Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1;318(4):L773-L786. doi: 10.1152/ajplung.00001.2020. Epub 2020 Mar 11. Am J Physiol Lung Cell Mol Physiol. 2020. PMID: 32159369 Free PMC article.
G6PD activity contributes to the regulation of histone acetylation and gene expression in smooth muscle cells and to the pathogenesis of vascular diseases.
Dhagia V, Kitagawa A, Jacob C, Zheng C, D'Alessandro A, Edwards JG, Rocic P, Gupte R, Gupte SA. Dhagia V, et al. Among authors: gupte sa, gupte r. Am J Physiol Heart Circ Physiol. 2021 Mar 1;320(3):H999-H1016. doi: 10.1152/ajpheart.00488.2020. Epub 2021 Jan 8. Am J Physiol Heart Circ Physiol. 2021. PMID: 33416454 Free PMC article.
107 results