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Intravitreal injection of a rationally designed AAV capsid library in non-human primate identifies variants with enhanced retinal transduction and neutralizing antibody evasion.
Kellish PC, Marsic D, Crosson SM, Choudhury S, Scalabrino ML, Strang CE, Hill J, McCullough KT, Peterson JJ, Fajardo D, Gupte S, Makal V, Kondratov O, Kondratova L, Iyer S, Witherspoon CD, Gamlin PD, Zolotukhin S, Boye SL, Boye SE. Kellish PC, et al. Among authors: gupte s. Mol Ther. 2023 Dec 6;31(12):3441-3456. doi: 10.1016/j.ymthe.2023.10.001. Epub 2023 Oct 9. Mol Ther. 2023. PMID: 37814449 Free article.
Global and endothelial G-protein coupled receptor 75 (GPR75) knockout relaxes pulmonary artery and mitigates hypoxia-induced pulmonary hypertension.
D'Addario CA, Matsumura S, Kitagawa A, Lainer GM, Zhang F, D'silva M, Khan MY, Froogh G, Gruzdev A, Zeldin DC, Schwartzman ML, Gupte SA. D'Addario CA, et al. Among authors: gupte sa. Vascul Pharmacol. 2023 Dec;153:107235. doi: 10.1016/j.vph.2023.107235. Epub 2023 Sep 23. Vascul Pharmacol. 2023. PMID: 37742819
334 results