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Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH.
Serpillon S, Floyd BC, Gupte RS, George S, Kozicky M, Neito V, Recchia F, Stanley W, Wolin MS, Gupte SA. Serpillon S, et al. Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H153-62. doi: 10.1152/ajpheart.01142.2008. Epub 2009 May 8. Am J Physiol Heart Circ Physiol. 2009. PMID: 19429815 Free PMC article.
Vascular smooth muscle cell contractile protein expression is increased through protein kinase G-dependent and -independent pathways by glucose-6-phosphate dehydrogenase inhibition and deficiency.
Chettimada S, Joshi SR, Dhagia V, Aiezza A 2nd, Lincoln TM, Gupte R, Miano JM, Gupte SA. Chettimada S, et al. Among authors: gupte sa, gupte r. Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H904-H912. doi: 10.1152/ajpheart.00335.2016. Epub 2016 Aug 12. Am J Physiol Heart Circ Physiol. 2016. PMID: 27521420 Free PMC article.
G6PD activity contributes to the regulation of histone acetylation and gene expression in smooth muscle cells and to the pathogenesis of vascular diseases.
Dhagia V, Kitagawa A, Jacob C, Zheng C, D'Alessandro A, Edwards JG, Rocic P, Gupte R, Gupte SA. Dhagia V, et al. Among authors: gupte r. Am J Physiol Heart Circ Physiol. 2021 Mar 1;320(3):H999-H1016. doi: 10.1152/ajpheart.00488.2020. Epub 2021 Jan 8. Am J Physiol Heart Circ Physiol. 2021. PMID: 33416454 Free PMC article.
Glucose-6-phosphate dehydrogenase plays a critical role in hypoxia-induced CD133+ progenitor cells self-renewal and stimulates their accumulation in the lungs of pulmonary hypertensive rats.
Chettimada S, Joshi SR, Alzoubi A, Gebb SA, McMurtry IF, Gupte R, Gupte SA. Chettimada S, et al. Among authors: gupte sa, gupte r. Am J Physiol Lung Cell Mol Physiol. 2014 Oct 1;307(7):L545-56. doi: 10.1152/ajplung.00303.2013. Epub 2014 Jul 25. Am J Physiol Lung Cell Mol Physiol. 2014. PMID: 25063801 Free PMC article.
CRISPR-Mediated Single Nucleotide Polymorphism Modeling in Rats Reveals Insight Into Reduced Cardiovascular Risk Associated With Mediterranean G6PD Variant.
Kitagawa A, Kizub I, Jacob C, Michael K, D'Alessandro A, Reisz JA, Grzybowski M, Geurts AM, Rocic P, Gupte R, Miano JM, Gupte SA. Kitagawa A, et al. Among authors: gupte sa, gupte r. Hypertension. 2020 Aug;76(2):523-532. doi: 10.1161/HYPERTENSIONAHA.120.14772. Epub 2020 Jun 8. Hypertension. 2020. PMID: 32507041 Free PMC article.
71 results