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MEK inhibition reprograms CD8+ T lymphocytes into memory stem cells with potent antitumor effects.
Verma V, Jafarzadeh N, Boi S, Kundu S, Jiang Z, Fan Y, Lopez J, Nandre R, Zeng P, Alolaqi F, Ahmad S, Gaur P, Barry ST, Valge-Archer VE, Smith PD, Banchereau J, Mkrtichyan M, Youngblood B, Rodriguez PC, Gupta S, Khleif SN. Verma V, et al. Among authors: gupta s. Nat Immunol. 2021 Jan;22(1):53-66. doi: 10.1038/s41590-020-00818-9. Epub 2020 Nov 23. Nat Immunol. 2021. PMID: 33230330 Free PMC article.
PI3K Isoforms in CD8+ T Cell Development and Function.
Gaur P, Mkrtichyan M, Verma V, Jafarzadeh N, Hattar M, Gupta S, Khleif SN. Gaur P, et al. Among authors: gupta s. Curr Top Microbiol Immunol. 2022;436:217-234. doi: 10.1007/978-3-031-06566-8_9. Curr Top Microbiol Immunol. 2022. PMID: 36243846
PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance.
Verma V, Shrimali RK, Ahmad S, Dai W, Wang H, Lu S, Nandre R, Gaur P, Lopez J, Sade-Feldman M, Yizhak K, Bjorgaard SL, Flaherty KT, Wargo JA, Boland GM, Sullivan RJ, Getz G, Hammond SA, Tan M, Qi J, Wong P, Merghoub T, Wolchok J, Hacohen N, Janik JE, Mkrtichyan M, Gupta S, Khleif SN. Verma V, et al. Among authors: gupta s. Nat Immunol. 2019 Sep;20(9):1231-1243. doi: 10.1038/s41590-019-0441-y. Epub 2019 Jul 29. Nat Immunol. 2019. PMID: 31358999 Free PMC article.
Author Correction: PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance.
Verma V, Shrimali RK, Ahmad S, Dai W, Wang H, Lu S, Nandre R, Gaur P, Lopez J, Sade-Feldman M, Yizhak K, Bjorgaard SL, Flaherty KT, Wargo JA, Boland GM, Sullivan RJ, Getz G, Hammond SA, Tan M, Qi J, Wong P, Merghoub T, Wolchok J, Hacohen N, Janik JE, Mkrtichyan M, Gupta S, Khleif SN. Verma V, et al. Among authors: gupta s. Nat Immunol. 2019 Nov;20(11):1555. doi: 10.1038/s41590-019-0519-6. Nat Immunol. 2019. PMID: 31551574
Emerging concepts in cancer therapy: Mechanisms of resistance.
Gupta S, Verma V, Dwarakanath BS. Gupta S, et al. Cancer Rep (Hoboken). 2022 Dec;5(12):e1715. doi: 10.1002/cnr2.1715. Epub 2022 Sep 9. Cancer Rep (Hoboken). 2022. PMID: 36083019 Free PMC article. No abstract available.
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