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Aminothiazoles: Hit to lead development to identify antileishmanial agents.
Bhuniya D, Mukkavilli R, Shivahare R, Launay D, Dere RT, Deshpande A, Verma A, Vishwakarma P, Moger M, Pradhan A, Pati H, Gopinath VS, Gupta S, Puri SK, Martin D. Bhuniya D, et al. Among authors: gupta s. Eur J Med Chem. 2015 Sep 18;102:582-93. doi: 10.1016/j.ejmech.2015.08.013. Epub 2015 Aug 11. Eur J Med Chem. 2015. PMID: 26318065
Synthesis, structure-activity relationships, and biological studies of chromenochalcones as potential antileishmanial agents.
Shivahare R, Korthikunta V, Chandasana H, Suthar MK, Agnihotri P, Vishwakarma P, Chaitanya TK, Kancharla P, Khaliq T, Gupta S, Bhatta RS, Pratap JV, Saxena JK, Gupta S, Tadigoppula N. Shivahare R, et al. Among authors: gupta s. J Med Chem. 2014 Apr 24;57(8):3342-57. doi: 10.1021/jm401893j. Epub 2014 Apr 2. J Med Chem. 2014. PMID: 24635539
Repositioning Antitubercular 6-Nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazoles for Neglected Tropical Diseases: Structure-Activity Studies on a Preclinical Candidate for Visceral Leishmaniasis.
Thompson AM, O'Connor PD, Blaser A, Yardley V, Maes L, Gupta S, Launay D, Martin D, Franzblau SG, Wan B, Wang Y, Ma Z, Denny WA. Thompson AM, et al. Among authors: gupta s. J Med Chem. 2016 Mar 24;59(6):2530-50. doi: 10.1021/acs.jmedchem.5b01699. Epub 2016 Mar 8. J Med Chem. 2016. PMID: 26901446 Free article.
7-Substituted 2-Nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazines: Novel Antitubercular Agents Lead to a New Preclinical Candidate for Visceral Leishmaniasis.
Thompson AM, O'Connor PD, Marshall AJ, Yardley V, Maes L, Gupta S, Launay D, Braillard S, Chatelain E, Franzblau SG, Wan B, Wang Y, Ma Z, Cooper CB, Denny WA. Thompson AM, et al. Among authors: gupta s. J Med Chem. 2017 May 25;60(10):4212-4233. doi: 10.1021/acs.jmedchem.7b00034. Epub 2017 May 11. J Med Chem. 2017. PMID: 28459575 Free PMC article.
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