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FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism.
Sakaguchi M, Cai W, Wang CH, Cederquist CT, Damasio M, Homan EP, Batista T, Ramirez AK, Gupta MK, Steger M, Wewer Albrechtsen NJ, Singh SK, Araki E, Mann M, Enerbäck S, Kahn CR. Sakaguchi M, et al. Among authors: gupta mk. Nat Commun. 2019 Apr 5;10(1):1582. doi: 10.1038/s41467-019-09418-0. Nat Commun. 2019. PMID: 30952843 Free PMC article.
Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling.
Softic S, Gupta MK, Wang GX, Fujisaka S, O'Neill BT, Rao TN, Willoughby J, Harbison C, Fitzgerald K, Ilkayeva O, Newgard CB, Cohen DE, Kahn CR. Softic S, et al. Among authors: gupta mk. J Clin Invest. 2017 Nov 1;127(11):4059-4074. doi: 10.1172/JCI94585. Epub 2017 Oct 3. J Clin Invest. 2017. PMID: 28972537 Free PMC article.
Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins.
Softic S, Meyer JG, Wang GX, Gupta MK, Batista TM, Lauritzen HPMM, Fujisaka S, Serra D, Herrero L, Willoughby J, Fitzgerald K, Ilkayeva O, Newgard CB, Gibson BW, Schilling B, Cohen DE, Kahn CR. Softic S, et al. Among authors: gupta mk. Cell Metab. 2019 Oct 1;30(4):735-753.e4. doi: 10.1016/j.cmet.2019.09.003. Cell Metab. 2019. PMID: 31577934 Free PMC article.
Leptin Receptor Signaling Regulates Protein Synthesis Pathways and Neuronal Differentiation in Pluripotent Stem Cells.
Gupta MK, Vethe H, Softic S, Rao TN, Wagh V, Shirakawa J, Barsnes H, Vaudel M, Takatani T, Kahraman S, Sakaguchi M, Martinez R, Hu J, Bjørlykke Y, Raeder H, Kulkarni RN. Gupta MK, et al. Stem Cell Reports. 2020 Nov 10;15(5):1067-1079. doi: 10.1016/j.stemcr.2020.10.001. Epub 2020 Oct 29. Stem Cell Reports. 2020. PMID: 33125875 Free PMC article.
Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD.
Park SH, Helsley RN, Fadhul T, Willoughby JLS, Noetzli L, Tu HC, Solheim MH, Fujisaka S, Pan H, Dreyfuss JM, Bons J, Rose J, King CD, Schilling B, Lusis AJ, Pan C, Gupta M, Kulkarni RN, Fitzgerald K, Kern PA, Divanovic S, Kahn CR, Softic S. Park SH, et al. Metabolism. 2023 Aug;145:155591. doi: 10.1016/j.metabol.2023.155591. Epub 2023 May 23. Metabolism. 2023. PMID: 37230214
Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling.
Softic S, Gupta MK, Wang GX, Fujisaka S, O'Neill BT, Rao TN, Willoughby J, Harbison C, Fitzgerald K, Ilkayeva O, Newgard CB, Cohen DE, Kahn CR. Softic S, et al. Among authors: gupta mk. J Clin Invest. 2018 Mar 1;128(3):1199. doi: 10.1172/JCI99009. Epub 2018 Mar 1. J Clin Invest. 2018. PMID: 29493547 Free PMC article. No abstract available.
962 results