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Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7-NLRP3 interaction.
Li Q, Feng H, Wang H, Wang Y, Mou W, Xu G, Zhang P, Li R, Shi W, Wang Z, Fang Z, Ren L, Wang Y, Lin L, Hou X, Dai W, Li Z, Wei Z, Liu T, Wang J, Guo Y, Li P, Zhao X, Zhan X, Xiao X, Bai Z. Li Q, et al. Among authors: guo y. EMBO Rep. 2022 Feb 3;23(2):e53499. doi: 10.15252/embr.202153499. Epub 2021 Dec 9. EMBO Rep. 2022. PMID: 34882936 Free PMC article.
Cis-stilbene glucoside in Polygonum multiflorum induces immunological idiosyncratic hepatotoxicity in LPS-treated rats by suppressing PPAR-γ.
Meng YK, Li CY, Li RY, He LZ, Cui HR, Yin P, Zhang CE, Li PY, Sang XX, Wang Y, Niu M, Zhang YM, Guo YM, Sun R, Wang JB, Bai ZF, Xiao XH. Meng YK, et al. Among authors: guo ym. Acta Pharmacol Sin. 2017 Oct;38(10):1340-1352. doi: 10.1038/aps.2017.32. Epub 2017 Jun 26. Acta Pharmacol Sin. 2017. PMID: 28649126 Free PMC article.
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