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Par14 protein associates with insulin receptor substrate 1 (IRS-1), thereby enhancing insulin-induced IRS-1 phosphorylation and metabolic actions.
Zhang J, Nakatsu Y, Shinjo T, Guo Y, Sakoda H, Yamamotoya T, Otani Y, Okubo H, Kushiyama A, Fujishiro M, Fukushima T, Tsuchiya Y, Kamata H, Iwashita M, Nishimura F, Katagiri H, Takahashi S, Kurihara H, Uchida T, Asano T. Zhang J, et al. Among authors: guo y. J Biol Chem. 2013 Jul 12;288(28):20692-701. doi: 10.1074/jbc.M113.485730. Epub 2013 May 29. J Biol Chem. 2013. PMID: 23720771 Free PMC article.
Macrophage foam cell formation is augmented in serum from patients with diabetic angiopathy.
Cui X, Kushiyama A, Yoneda M, Nakatsu Y, Guo Y, Zhang J, Ono H, Kanna M, Sakoda H, Ono H, Kikuchi T, Fujishiro M, Shiomi M, Kamata H, Kurihara H, Kikuchi M, Kawazu S, Nishimura F, Asano T. Cui X, et al. Among authors: guo y. Diabetes Res Clin Pract. 2010 Jan;87(1):57-63. doi: 10.1016/j.diabres.2009.10.011. Epub 2009 Nov 24. Diabetes Res Clin Pract. 2010. PMID: 19939487
Decreased SIRT1 expression and LKB1 phosphorylation occur with long-term high-fat diet feeding, in addition to AMPK phosphorylation impairment in the early phase.
Yoneda M, Guo Y, Ono H, Nakatsu Y, Zhang J, Cui X, Iwashita M, Kumamoto S, Tsuchiya Y, Sakoda H, Fujishiro M, Kushiyama A, Koketsu Y, Kikuchi T, Kamata H, Nishimura F, Asano T. Yoneda M, et al. Among authors: guo y. Obes Res Clin Pract. 2010 Jul-Sep;4(3):e163-246. doi: 10.1016/j.orcp.2010.02.002. Obes Res Clin Pract. 2010. PMID: 24345663
Role of Pin1 protein in the pathogenesis of nonalcoholic steatohepatitis in a rodent model.
Nakatsu Y, Otani Y, Sakoda H, Zhang J, Guo Y, Okubo H, Kushiyama A, Fujishiro M, Kikuch T, Fukushima T, Ohno H, Tsuchiya Y, Kamata H, Nagamachi A, Inaba T, Nishimura F, Katagiri H, Takahashi S, Kurihara H, Uchida T, Asano T. Nakatsu Y, et al. Among authors: guo y. J Biol Chem. 2012 Dec 28;287(53):44526-35. doi: 10.1074/jbc.M112.397133. Epub 2012 Oct 29. J Biol Chem. 2012. PMID: 23112047 Free PMC article.
Angiotensin receptor 1 blocker valsartan normalizes gene expression profiles of 3T3-L1 adipocytes altered by co-culture with LPS-treated RAW264.7 macrophages.
Kumamoto S, Kushiyama A, Nakatsu Y, Sakoda H, Fujishiro M, Iwashita M, Ohno H, Zhang J, Guo Y, Aburatani H, Kamata H, Nishimura F, Asano T. Kumamoto S, et al. Among authors: guo y. Obes Res Clin Pract. 2012 Oct-Dec;6(4):e263-346. doi: 10.1016/j.orcp.2012.05.005. Obes Res Clin Pract. 2012. PMID: 24331589
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