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Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene.
Pineda SS, Chin YK, Undheim EAB, Senff S, Mobli M, Dauly C, Escoubas P, Nicholson GM, Kaas Q, Guo S, Herzig V, Mattick JS, King GF. Pineda SS, et al. Among authors: guo s. Proc Natl Acad Sci U S A. 2020 May 26;117(21):11399-11408. doi: 10.1073/pnas.1914536117. Epub 2020 May 12. Proc Natl Acad Sci U S A. 2020. PMID: 32398368 Free PMC article.
Towards a generic prototyping approach for therapeutically-relevant peptides and proteins in a cell-free translation system.
Wu Y, Cui Z, Huang YH, de Veer SJ, Aralov AV, Guo Z, Moradi SV, Hinton AO, Deuis JR, Guo S, Chen KE, Collins BM, Vetter I, Herzig V, Jones A, Cooper MA, King GF, Craik DJ, Alexandrov K, Mureev S. Wu Y, et al. Among authors: guo s, guo z. Nat Commun. 2022 Jan 11;13(1):260. doi: 10.1038/s41467-021-27854-9. Nat Commun. 2022. PMID: 35017494 Free PMC article.
Genomic, functional and structural analyses elucidate evolutionary innovation within the sea anemone 8 toxin family.
Ashwood LM, Elnahriry KA, Stewart ZK, Shafee T, Naseem MU, Szanto TG, van der Burg CA, Smith HL, Surm JM, Undheim EAB, Madio B, Hamilton BR, Guo S, Wai DCC, Coyne VL, Phillips MJ, Dudley KJ, Hurwood DA, Panyi G, King GF, Pavasovic A, Norton RS, Prentis PJ. Ashwood LM, et al. Among authors: guo s. BMC Biol. 2023 May 24;21(1):121. doi: 10.1186/s12915-023-01617-y. BMC Biol. 2023. PMID: 37226201 Free PMC article.
Structural and functional characterisation of Tst2, a novel TRPV1 inhibitory peptide from the Australian sea anemone Telmatactis stephensoni.
Elnahriry KA, Wai DCC, Ashwood LM, Naseem MU, Szanto TG, Guo S, Panyi G, Prentis PJ, Norton RS. Elnahriry KA, et al. Among authors: guo s. Biochim Biophys Acta Proteins Proteom. 2024 Jan 1;1872(1):140952. doi: 10.1016/j.bbapap.2023.140952. Epub 2023 Aug 26. Biochim Biophys Acta Proteins Proteom. 2024. PMID: 37640250 Free article.
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