E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1.
Duan C, Li Y, Zhi H, Tian Y, Huang Z, Chen S, Zhang Y, Liu Q, Zhou L, Jiang X, Ullah K, Guo Q, Liu Z, Xu Y, Han J, Hou J, O'Connor DP, Xu GQ.
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Acta Pharmacol Sin. 2024 May 13. doi: 10.1038/s41401-024-01290-z. Online ahead of print.
Acta Pharmacol Sin. 2024.
PMID: 38740904