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Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.
Guo JY, Chen HY, Mathew R, Fan J, Strohecker AM, Karsli-Uzunbas G, Kamphorst JJ, Chen G, Lemons JM, Karantza V, Coller HA, Dipaola RS, Gelinas C, Rabinowitz JD, White E. Guo JY, et al. Genes Dev. 2011 Mar 1;25(5):460-70. doi: 10.1101/gad.2016311. Epub 2011 Feb 11. Genes Dev. 2011. PMID: 21317241 Free PMC article.
Autophagy is required for glucose homeostasis and lung tumor maintenance.
Karsli-Uzunbas G, Guo JY, Price S, Teng X, Laddha SV, Khor S, Kalaany NY, Jacks T, Chan CS, Rabinowitz JD, White E. Karsli-Uzunbas G, et al. Among authors: guo jy. Cancer Discov. 2014 Aug;4(8):914-27. doi: 10.1158/2159-8290.CD-14-0363. Epub 2014 May 29. Cancer Discov. 2014. PMID: 24875857 Free PMC article.
Autophagy maintains tumour growth through circulating arginine.
Poillet-Perez L, Xie X, Zhan L, Yang Y, Sharp DW, Hu ZS, Su X, Maganti A, Jiang C, Lu W, Zheng H, Bosenberg MW, Mehnert JM, Guo JY, Lattime E, Rabinowitz JD, White E. Poillet-Perez L, et al. Among authors: guo jy. Nature. 2018 Nov;563(7732):569-573. doi: 10.1038/s41586-018-0697-7. Epub 2018 Nov 14. Nature. 2018. PMID: 30429607 Free PMC article.
Author Correction: Autophagy maintains tumour growth through circulating arginine.
Poillet-Perez L, Xie X, Zhan L, Yang Y, Sharp DW, Hu ZS, Su X, Maganti A, Jiang C, Lu W, Zheng H, Bosenberg MW, Mehnert JM, Guo JY, Lattime E, Rabinowitz JD, White E. Poillet-Perez L, et al. Among authors: guo jy. Nature. 2019 Jan;565(7737):E3. doi: 10.1038/s41586-018-0815-6. Nature. 2019. PMID: 30523330
560 results