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Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses.
Zhou X, Zhao C, Xu H, Xu Y, Zhan L, Wang P, He J, Lu T, Gu Y, Yang Y, Xu C, Chen Y, Liu Y, Zeng Y, Tian F, Chen Q, Xie X, Liu J, Hu H, Li J, Zheng Y, Guo J, Gao Z. Zhou X, et al. Among authors: guo j. Nat Chem Biol. 2024 Feb 14. doi: 10.1038/s41589-024-01555-y. Online ahead of print. Nat Chem Biol. 2024. PMID: 38355723
Ligand activation mechanisms of human KCNQ2 channel.
Ma D, Zheng Y, Li X, Zhou X, Yang Z, Zhang Y, Wang L, Zhang W, Fang J, Zhao G, Hou P, Nan F, Yang W, Su N, Gao Z, Guo J. Ma D, et al. Among authors: guo j. Nat Commun. 2023 Oct 19;14(1):6632. doi: 10.1038/s41467-023-42416-x. Nat Commun. 2023. PMID: 37857637 Free PMC article.
Structures and mechanisms of the Arabidopsis auxin transporter PIN3.
Su N, Zhu A, Tao X, Ding ZJ, Chang S, Ye F, Zhang Y, Zhao C, Chen Q, Wang J, Zhou CY, Guo Y, Jiao S, Zhang S, Wen H, Ma L, Ye S, Zheng SJ, Yang F, Wu S, Guo J. Su N, et al. Among authors: guo y, guo j. Nature. 2022 Sep;609(7927):616-621. doi: 10.1038/s41586-022-05142-w. Epub 2022 Aug 2. Nature. 2022. PMID: 35917926
Structures of a mammalian TRPM8 in closed state.
Zhao C, Xie Y, Xu L, Ye F, Xu X, Yang W, Yang F, Guo J. Zhao C, et al. Among authors: guo j. Nat Commun. 2022 Jun 3;13(1):3113. doi: 10.1038/s41467-022-30919-y. Nat Commun. 2022. PMID: 35662242 Free PMC article.
A small-molecule activation mechanism that directly opens the KCNQ2 channel.
Zhang S, Ma D, Wang K, Li Y, Yang Z, Li X, Li J, He J, Mei L, Ye Y, Chen Z, Shen J, Hou P, Guo J, Zhang Q, Yang H. Zhang S, et al. Among authors: guo j. Nat Chem Biol. 2024 Jan 2. doi: 10.1038/s41589-023-01515-y. Online ahead of print. Nat Chem Biol. 2024. PMID: 38167918
Structural basis for the gating modulation of Kv4.3 by auxiliary subunits.
Ma D, Zhao C, Wang X, Li X, Zha Y, Zhang Y, Fu G, Liang P, Guo J, Lai D. Ma D, et al. Among authors: guo j. Cell Res. 2022 Apr;32(4):411-414. doi: 10.1038/s41422-021-00608-4. Epub 2022 Jan 7. Cell Res. 2022. PMID: 34997220 Free PMC article. No abstract available.
29,046 results
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