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Photoreceptor laminin drives differentiation of human pluripotent stem cells to photoreceptor progenitors that partially restore retina function.
Tay HG, Andre H, Chrysostomou V, Adusumalli S, Guo J, Ren X, Tan WS, Tor JE, Moreno-Moral A, Plastino F, Bartuma H, Cai Z, Tun SBB, Barathi VA, Siew Wei GT, Grenci G, Chong LY, Holmgren A, Kvanta A, Crowston JG, Petretto E, Tryggvason K. Tay HG, et al. Among authors: guo j. Mol Ther. 2023 Mar 1;31(3):825-846. doi: 10.1016/j.ymthe.2022.12.012. Epub 2023 Jan 12. Mol Ther. 2023. PMID: 36638800 Free PMC article.
A meta-analysis of expression signatures in glomerular disease.
Tryggvason SH, Guo J, Nukui M, Norlin J, Haraldsson B, Jörnvall H, Tryggvason K, He L. Tryggvason SH, et al. Among authors: guo j. Kidney Int. 2013 Sep;84(3):591-9. doi: 10.1038/ki.2013.169. Epub 2013 Jun 19. Kidney Int. 2013. PMID: 23783239 Free article.
Lmx1b and FoxC combinatorially regulate podocin expression in podocytes.
He B, Ebarasi L, Zhao Z, Guo J, Ojala JR, Hultenby K, De Val S, Betsholtz C, Tryggvason K. He B, et al. Among authors: guo j. J Am Soc Nephrol. 2014 Dec;25(12):2764-77. doi: 10.1681/ASN.2012080823. Epub 2014 May 22. J Am Soc Nephrol. 2014. PMID: 24854274 Free PMC article.
Whole-Genome Sequencing of Finnish Type 1 Diabetic Siblings Discordant for Kidney Disease Reveals DNA Variants associated with Diabetic Nephropathy.
Guo J, Rackham OJL, Sandholm N, He B, Österholm AM, Valo E, Harjutsalo V, Forsblom C, Toppila I, Parkkonen M, Li Q, Zhu W, Harmston N, Chothani S, Öhman MK, Eng E, Sun Y, Petretto E, Groop PH, Tryggvason K. Guo J, et al. J Am Soc Nephrol. 2020 Feb;31(2):309-323. doi: 10.1681/ASN.2019030289. Epub 2020 Jan 9. J Am Soc Nephrol. 2020. PMID: 31919106 Free PMC article.
WWP2 Regulates Renal Fibrosis and the Metabolic Reprogramming of Profibrotic Myofibroblasts.
Chen H, You R, Guo J, Zhou W, Chew G, Devapragash N, Loh JZ, Gesualdo L, Li Y, Jiang Y, Tan ELS, Chen S, Pontrelli P, Pesce F, Behmoaras J, Zhang A, Petretto E. Chen H, et al. Among authors: guo j. J Am Soc Nephrol. 2024 Mar 19. doi: 10.1681/ASN.0000000000000328. Online ahead of print. J Am Soc Nephrol. 2024. PMID: 38502123 No abstract available.
A CRISP(e)R view on kidney organoids allows generation of an induced pluripotent stem cell-derived kidney model for drug discovery.
Boreström C, Jonebring A, Guo J, Palmgren H, Cederblad L, Forslöw A, Svensson A, Söderberg M, Reznichenko A, Nyström J, Patrakka J, Hicks R, Maresca M, Valastro B, Collén A. Boreström C, et al. Among authors: guo j. Kidney Int. 2018 Dec;94(6):1099-1110. doi: 10.1016/j.kint.2018.05.003. Epub 2018 Jul 31. Kidney Int. 2018. PMID: 30072040 Free article.
MYC is downregulated by a mitochondrial checkpoint mechanism.
Zhang X, Mofers A, Hydbring P, Olofsson MH, Guo J, Linder S, D'Arcy P. Zhang X, et al. Among authors: guo j. Oncotarget. 2017 Oct 6;8(52):90225-90237. doi: 10.18632/oncotarget.21653. eCollection 2017 Oct 27. Oncotarget. 2017. PMID: 29163823 Free PMC article.
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