Guo J - Search Results

1

Synthesis and biological evaluation of heterocyclic carboxylic acyl shikonin derivatives.

Wang XM, Lin HY, Kong WY, Guo J, Shi J, Huang SC, Qi JL, Yang RW, Gu HW, Yang YH. Wang XM, et al. Among authors: guo j. Chem Biol Drug Des. 2014 Mar;83(3):334-43. doi: 10.1111/cbdd.12247. Epub 2013 Dec 26. Chem Biol Drug Des. 2014. PMID: 24118825

2

Novel shikonin derivatives targeting tubulin as anticancer agents.

Guo J, Chen XF, Liu J, Lin HY, Han HW, Liu HC, Huang SC, Shahla BK, Kulek A, Qi JL, Wang XM, Ling LJ, Yang YH. Guo J, et al. Chem Biol Drug Des. 2014 Nov;84(5):603-15. doi: 10.1111/cbdd.12353. Epub 2014 Jul 3. Chem Biol Drug Des. 2014. PMID: 24797889

3

Design, synthesis and biological evaluation of 1-phenanthryl-tetrahydroisoquinoline derivatives as novel p21-activated kinase 4 (PAK4) inhibitors.

Song S, Li X, Guo J, Hao C, Feng Y, Guo B, Liu T, Zhang Q, Zhang Z, Li R, Wang J, Lin B, Li F, Zhao D, Cheng M. Song S, et al. Among authors: guo b, guo j. Org Biomol Chem. 2015 Mar 28;13(12):3803-18. doi: 10.1039/c5ob00037h. Org Biomol Chem. 2015. PMID: 25705811

4

Discovery of indolin-2-one derivatives as potent PAK4 inhibitors: Structure-activity relationship analysis, biological evaluation and molecular docking study.

Guo J, Zhu M, Wu T, Hao C, Wang K, Yan Z, Huang W, Wang J, Zhao D, Cheng M. Guo J, et al. Bioorg Med Chem. 2017 Jul 1;25(13):3500-3511. doi: 10.1016/j.bmc.2017.04.047. Epub 2017 May 3. Bioorg Med Chem. 2017. PMID: 28502459

5

Development of novel β-carboline-based hydroxamate derivatives as HDAC inhibitors with antiproliferative and antimetastatic activities in human cancer cells.

Ling Y, Guo J, Yang Q, Zhu P, Miao J, Gao W, Peng Y, Yang J, Xu K, Xiong B, Liu G, Tao J, Luo L, Zhu Q, Zhang Y. Ling Y, et al. Among authors: guo j. Eur J Med Chem. 2018 Jan 20;144:398-409. doi: 10.1016/j.ejmech.2017.12.061. Epub 2017 Dec 20. Eur J Med Chem. 2018. PMID: 29288941

6

Design, synthesis and biological evaluation of novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potential FAK inhibitors and anticancer agents.

Wang R, Chen Y, Zhao X, Yu S, Yang B, Wu T, Guo J, Hao C, Zhao D, Cheng M. Wang R, et al. Among authors: guo j. Eur J Med Chem. 2019 Dec 1;183:111716. doi: 10.1016/j.ejmech.2019.111716. Epub 2019 Sep 18. Eur J Med Chem. 2019. PMID: 31550660

7

Design, synthesis and biological evaluation of novel benzoxaborole derivatives as potent PDE4 inhibitors for topical treatment of atopic dermatitis.

Chu Z, Xu Q, Zhu Q, Ma X, Mo J, Lin G, Zhao Y, Gu Y, Bian L, Shao L, Guo J, Ye W, Li J, He G, Xu Y. Chu Z, et al. Among authors: guo j. Eur J Med Chem. 2021 Mar 5;213:113171. doi: 10.1016/j.ejmech.2021.113171. Epub 2021 Jan 12. Eur J Med Chem. 2021. PMID: 33482600

8

Development of 2, 4-diaminoquinazoline derivatives as potent PAK4 inhibitors by the core refinement strategy.

Hao C, Huang W, Li X, Guo J, Chen M, Yan Z, Wang K, Jiang X, Song S, Wang J, Zhao D, Li F, Cheng M. Hao C, et al. Among authors: guo j. Eur J Med Chem. 2017 May 5;131:1-13. doi: 10.1016/j.ejmech.2017.02.063. Epub 2017 Mar 8. Eur J Med Chem. 2017. PMID: 28284095

9

Design and Synthesis of C3-Substituted β-Carboline-Based Histone Deacetylase Inhibitors with Potent Antitumor Activities.

Ling Y, Feng J, Luo L, Guo J, Peng Y, Wang T, Ge X, Xu Q, Wang X, Dai H, Zhang Y. Ling Y, et al. Among authors: guo j. ChemMedChem. 2017 May 9;12(9):646-651. doi: 10.1002/cmdc.201700133. Epub 2017 Apr 20. ChemMedChem. 2017. PMID: 28425177

10

A novel harmine derivative, N-(4-(hydroxycarbamoyl)benzyl)-1-(4- methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxamide (HBC), as histone deacetylase inhibitor: in vitro antiproliferation, apoptosis induction, cell cycle arrest, and antimetastatic effects.

Miao JF, Peng YF, Chen S, Gao WJ, Yang QX, Zhu P, Guo J, Tao J, Luo L, Zhang Y, Ling Y. Miao JF, et al. Among authors: guo j. Eur J Pharmacol. 2018 Apr 5;824:78-88. doi: 10.1016/j.ejphar.2018.02.004. Epub 2018 Feb 9. Eur J Pharmacol. 2018. PMID: 29428472

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