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SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology.
Huang J, Wu C, Kloeber JA, Gao H, Gao M, Zhu Q, Chang Y, Zhao F, Guo G, Luo K, Dai H, Liu S, Huang Q, Kim W, Zhou Q, Zhu S, Wu Z, Tu X, Yin P, Deng M, Wang L, Yuan J, Lou Z. Huang J, et al. Among authors: guo g. Mol Cell. 2023 Apr 6;83(7):1043-1060.e10. doi: 10.1016/j.molcel.2023.02.004. Epub 2023 Feb 27. Mol Cell. 2023. PMID: 36854302 Free PMC article.
ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection.
Zhao F, Kim W, Gao H, Liu C, Zhang Y, Chen Y, Deng M, Zhou Q, Huang J, Hu Q, Chen SH, Nowsheen S, Kloeber JA, Qin B, Yin P, Tu X, Guo G, Qin S, Zhang C, Gao M, Luo K, Liu Y, Lou Z, Yuan J. Zhao F, et al. Among authors: guo g. Nat Cell Biol. 2021 Aug;23(8):894-904. doi: 10.1038/s41556-021-00723-9. Epub 2021 Aug 5. Nat Cell Biol. 2021. PMID: 34354233
USP13 regulates the replication stress response by deubiquitinating TopBP1.
Kim W, Zhao F, Gao H, Qin S, Hou J, Deng M, Kloeber JA, Huang J, Zhou Q, Guo G, Gao M, Zeng X, Zhu S, Tu X, Wu Z, Zhang Y, Yin P, Kaufmann SH, Luo K, Lou Z. Kim W, et al. Among authors: guo g. DNA Repair (Amst). 2021 Apr;100:103063. doi: 10.1016/j.dnarep.2021.103063. Epub 2021 Feb 6. DNA Repair (Amst). 2021. PMID: 33592542 Free PMC article.
DOCK7 protects against replication stress by promoting RPA stability on chromatin.
Gao M, Guo G, Huang J, Hou X, Ham H, Kim W, Zhao F, Tu X, Zhou Q, Zhang C, Zhu Q, Liu J, Yan Y, Xu Z, Yin P, Luo K, Weroha J, Deng M, Billadeau DD, Lou Z. Gao M, et al. Among authors: guo g. Nucleic Acids Res. 2021 Apr 6;49(6):3322-3337. doi: 10.1093/nar/gkab134. Nucleic Acids Res. 2021. PMID: 33704464 Free PMC article.
METTL16 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in pancreatic ductal adenocarcinoma.
Zeng X, Zhao F, Cui G, Zhang Y, Deshpande RA, Chen Y, Deng M, Kloeber JA, Shi Y, Zhou Q, Zhang C, Hou J, Kim W, Tu X, Yan Y, Xu Z, Chen L, Gao H, Guo G, Liu J, Zhu Q, Cao Y, Huang J, Wu Z, Zhu S, Yin P, Luo K, Mer G, Paull TT, Yuan J, Tao K, Lou Z. Zeng X, et al. Among authors: guo g. Nat Cancer. 2022 Sep;3(9):1088-1104. doi: 10.1038/s43018-022-00429-3. Epub 2022 Sep 22. Nat Cancer. 2022. PMID: 36138131
4,254 results