Gunosewoyo H - Search Results

1

Evaluation of Protein Kinase Inhibitors with PLK4 Cross-Over Potential in a Pre-Clinical Model of Cancer.

Suri A, Bailey AW, Tavares MT, Gunosewoyo H, Dyer CP, Grupenmacher AT, Piper DR, Horton RA, Tomita T, Kozikowski AP, Roy SM, Sredni ST. Suri A, et al. Among authors: gunosewoyo h. Int J Mol Sci. 2019 Apr 29;20(9):2112. doi: 10.3390/ijms20092112. Int J Mol Sci. 2019. PMID: 31035676 Free PMC article.

2

Identification of a glycogen synthase kinase-3β inhibitor that attenuates hyperactivity in CLOCK mutant mice.

Kozikowski AP, Gunosewoyo H, Guo S, Gaisina IN, Walter RL, Ketcherside A, McClung CA, Mesecar AD, Caldarone B. Kozikowski AP, et al. Among authors: gunosewoyo h. ChemMedChem. 2011 Sep 5;6(9):1593-602. doi: 10.1002/cmdc.201100188. Epub 2011 Jul 5. ChemMedChem. 2011. PMID: 21732538 Free PMC article.

3

Structure-guided design of a highly selective glycogen synthase kinase-3β inhibitor: a superior neuroprotective pyrazolone showing antimania effects.

Chen W, Gaisina IN, Gunosewoyo H, Malekiani SA, Hanania T, Kozikowski AP. Chen W, et al. Among authors: gunosewoyo h. ChemMedChem. 2011 Sep 5;6(9):1587-92. doi: 10.1002/cmdc.201100231. Epub 2011 Jul 12. ChemMedChem. 2011. PMID: 21751402 Free PMC article. No abstract available.

4

Structural analogs of huperzine A improve survival in guinea pigs exposed to soman.

Gunosewoyo H, Tipparaju SK, Pieroni M, Wang Y, Doctor BP, Nambiar MP, Kozikowski AP. Gunosewoyo H, et al. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1544-7. doi: 10.1016/j.bmcl.2012.11.083. Epub 2012 Dec 1. Bioorg Med Chem Lett. 2013. PMID: 23395652

5

Preliminary structure-activity relationships and biological evaluation of novel antitubercular indolecarboxamide derivatives against drug-susceptible and drug-resistant Mycobacterium tuberculosis strains.

Onajole OK, Pieroni M, Tipparaju SK, Lun S, Stec J, Chen G, Gunosewoyo H, Guo H, Ammerman NC, Bishai WR, Kozikowski AP. Onajole OK, et al. Among authors: gunosewoyo h. J Med Chem. 2013 May 23;56(10):4093-103. doi: 10.1021/jm4003878. Epub 2013 May 3. J Med Chem. 2013. PMID: 23611124

6

From α4β2 Nicotinic Ligands to the Discovery of σ1 Receptor Ligands: Pharmacophore Analysis and Rational Design.

Yu LF, Zhang HK, Gunosewoyo H, Kozikowski AP. Yu LF, et al. Among authors: gunosewoyo h. ACS Med Chem Lett. 2012 Dec 13;3(12):1054-1058. doi: 10.1021/ml3002715. ACS Med Chem Lett. 2012. PMID: 23641311 Free PMC article.

7

Characterization of maleimide-based glycogen synthase kinase-3 (GSK-3) inhibitors as stimulators of steroidogenesis.

Gunosewoyo H, Midzak A, Gaisina IN, Sabath EV, Fedolak A, Hanania T, Brunner D, Papadopoulos V, Kozikowski AP. Gunosewoyo H, et al. J Med Chem. 2013 Jun 27;56(12):5115-29. doi: 10.1021/jm400511s. Epub 2013 Jun 17. J Med Chem. 2013. PMID: 23725591 Free PMC article.

8

Inhibition of GSK-3 induces differentiation and impaired glucose metabolism in renal cancer.

Pal K, Cao Y, Gaisina IN, Bhattacharya S, Dutta SK, Wang E, Gunosewoyo H, Kozikowski AP, Billadeau DD, Mukhopadhyay D. Pal K, et al. Among authors: gunosewoyo h. Mol Cancer Ther. 2014 Feb;13(2):285-96. doi: 10.1158/1535-7163.MCT-13-0681. Epub 2013 Dec 10. Mol Cancer Ther. 2014. PMID: 24327518 Free PMC article.

9

Optimization of 2-phenylcyclopropylmethylamines as selective serotonin 2C receptor agonists and their evaluation as potential antipsychotic agents.

Cheng J, Giguère PM, Onajole OK, Lv W, Gaisin A, Gunosewoyo H, Schmerberg CM, Pogorelov VM, Rodriguiz RM, Vistoli G, Wetsel WC, Roth BL, Kozikowski AP. Cheng J, et al. Among authors: gunosewoyo h. J Med Chem. 2015 Feb 26;58(4):1992-2002. doi: 10.1021/jm5019274. Epub 2015 Feb 10. J Med Chem. 2015. PMID: 25633969 Free PMC article.

10

Synthesis and biological evaluation of novel hybrids of highly potent and selective α4β2-Nicotinic acetylcholine receptor (nAChR) partial agonists.

Zhang HK, Eaton JB, Fedolak A, Gunosewoyo H, Onajole OK, Brunner D, Lukas RJ, Yu LF, Kozikowski AP. Zhang HK, et al. Among authors: gunosewoyo h. Eur J Med Chem. 2016 Nov 29;124:689-697. doi: 10.1016/j.ejmech.2016.09.016. Epub 2016 Sep 9. Eur J Med Chem. 2016. PMID: 27639361 Free PMC article.

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