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Quercetin inhibits glucose transport by binding to an exofacial site on GLUT1.
Hamilton KE, Rekman JF, Gunnink LK, Busscher BM, Scott JL, Tidball AM, Stehouwer NR, Johnecheck GN, Looyenga BD, Louters LL. Hamilton KE, et al. Among authors: gunnink lk. Biochimie. 2018 Aug;151:107-114. doi: 10.1016/j.biochi.2018.05.012. Epub 2018 May 29. Biochimie. 2018. PMID: 29857184 Free PMC article.
Curcumin directly inhibits the transport activity of GLUT1.
Gunnink LK, Alabi OD, Kuiper BD, Gunnink SM, Schuiteman SJ, Strohbehn LE, Hamilton KE, Wrobel KE, Louters LL. Gunnink LK, et al. Biochimie. 2016 Jun;125:179-85. doi: 10.1016/j.biochi.2016.03.014. Epub 2016 Mar 31. Biochimie. 2016. PMID: 27039889 Free PMC article.