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Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status.
Lyons PA, Peters JE, Alberici F, Liley J, Coulson RMR, Astle W, Baldini C, Bonatti F, Cid MC, Elding H, Emmi G, Epplen J, Guillevin L, Jayne DRW, Jiang T, Gunnarsson I, Lamprecht P, Leslie S, Little MA, Martorana D, Moosig F, Neumann T, Ohlsson S, Quickert S, Ramirez GA, Rewerska B, Schett G, Sinico RA, Szczeklik W, Tesar V, Vukcevic D; European Vasculitis Genetics Consortium; Terrier B, Watts RA, Vaglio A, Holle JU, Wallace C, Smith KGC. Lyons PA, et al. Among authors: gunnarsson i. Nat Commun. 2019 Nov 12;10(1):5120. doi: 10.1038/s41467-019-12515-9. Nat Commun. 2019. PMID: 31719529 Free PMC article.
Copy number, linkage disequilibrium and disease association in the FCGR locus.
Niederer HA, Willcocks LC, Rayner TF, Yang W, Lau YL, Williams TN, Scott JA, Urban BC, Peshu N, Dunstan SJ, Hien TT, Phu NH, Padyukov L, Gunnarsson I, Svenungsson E, Savage CO, Watts RA, Lyons PA, Clayton DG, Smith KG. Niederer HA, et al. Among authors: gunnarsson i. Hum Mol Genet. 2010 Aug 15;19(16):3282-94. doi: 10.1093/hmg/ddq216. Epub 2010 May 27. Hum Mol Genet. 2010. PMID: 20508037 Free PMC article.
A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE.
Sandling JK, Garnier S, Sigurdsson S, Wang C, Nordmark G, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Truedsson L, Eriksson C, Rantapää-Dahlqvist S, Mälarstig A, Strawbridge RJ, Hamsten A, Criswell LA, Graham RR, Behrens TW, Eloranta ML, Alm G, Rönnblom L, Syvänen AC. Sandling JK, et al. Among authors: gunnarsson i. Eur J Hum Genet. 2011 Apr;19(4):479-84. doi: 10.1038/ejhg.2010.197. Epub 2010 Dec 22. Eur J Hum Genet. 2011. PMID: 21179067 Free PMC article.
Genetically distinct subsets within ANCA-associated vasculitis.
Lyons PA, Rayner TF, Trivedi S, Holle JU, Watts RA, Jayne DR, Baslund B, Brenchley P, Bruchfeld A, Chaudhry AN, Cohen Tervaert JW, Deloukas P, Feighery C, Gross WL, Guillevin L, Gunnarsson I, Harper L, Hrušková Z, Little MA, Martorana D, Neumann T, Ohlsson S, Padmanabhan S, Pusey CD, Salama AD, Sanders JS, Savage CO, Segelmark M, Stegeman CA, Tesař V, Vaglio A, Wieczorek S, Wilde B, Zwerina J, Rees AJ, Clayton DG, Smith KG. Lyons PA, et al. Among authors: gunnarsson i. N Engl J Med. 2012 Jul 19;367(3):214-23. doi: 10.1056/NEJMoa1108735. N Engl J Med. 2012. PMID: 22808956 Free PMC article.
Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations.
Wang C, Ahlford A, Järvinen TM, Nordmark G, Eloranta ML, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Truedsson L, Eriksson C, Rantapää-Dahlqvist S, Sjöwall C, Julkunen H, Criswell LA, Graham RR, Behrens TW, Kere J, Rönnblom L, Syvänen AC, Sandling JK. Wang C, et al. Among authors: gunnarsson i. Eur J Hum Genet. 2013 Sep;21(9):994-9. doi: 10.1038/ejhg.2012.277. Epub 2012 Dec 19. Eur J Hum Genet. 2013. PMID: 23249952 Free PMC article.
A research study of the association between maternal microchimerism and systemic lupus erythematosus in adults: a comparison between patients and healthy controls based on single-nucleotide polymorphism using quantitative real-time PCR.
Kanold AM, Svenungsson E, Gunnarsson I, Götherström C, Padyukov L, Papadogiannakis N, Uzunel M, Westgren M. Kanold AM, et al. Among authors: gunnarsson i. PLoS One. 2013 Sep 11;8(9):e74534. doi: 10.1371/journal.pone.0074534. eCollection 2013. PLoS One. 2013. PMID: 24040274 Free PMC article.
241 results