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PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment: recommendations from a joint EPAA--EURL ECVAM ADME workshop.
Bessems JG, Loizou G, Krishnan K, Clewell HJ 3rd, Bernasconi C, Bois F, Coecke S, Collnot EM, Diembeck W, Farcal LR, Geraets L, Gundert-Remy U, Kramer N, Küsters G, Leite SB, Pelkonen OR, Schröder K, Testai E, Wilk-Zasadna I, Zaldívar-Comenges JM. Bessems JG, et al. Regul Toxicol Pharmacol. 2014 Feb;68(1):119-39. doi: 10.1016/j.yrtph.2013.11.008. Epub 2013 Nov 26. Regul Toxicol Pharmacol. 2014. PMID: 24287156
Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.
Adler S, Basketter D, Creton S, Pelkonen O, van Benthem J, Zuang V, Andersen KE, Angers-Loustau A, Aptula A, Bal-Price A, Benfenati E, Bernauer U, Bessems J, Bois FY, Boobis A, Brandon E, Bremer S, Broschard T, Casati S, Coecke S, Corvi R, Cronin M, Daston G, Dekant W, Felter S, Grignard E, Gundert-Remy U, Heinonen T, Kimber I, Kleinjans J, Komulainen H, Kreiling R, Kreysa J, Leite SB, Loizou G, Maxwell G, Mazzatorta P, Munn S, Pfuhler S, Phrakonkham P, Piersma A, Poth A, Prieto P, Repetto G, Rogiers V, Schoeters G, Schwarz M, Serafimova R, Tähti H, Testai E, van Delft J, van Loveren H, Vinken M, Worth A, Zaldivar JM. Adler S, et al. Arch Toxicol. 2011 May;85(5):367-485. doi: 10.1007/s00204-011-0693-2. Epub 2011 May 1. Arch Toxicol. 2011. PMID: 21533817 Review.
Physiologically-based Kinetic Modelling (PBK Modelling): meeting the 3Rs agenda. The report and recommendations of ECVAM Workshop 63.
Bouvier d'Yvoire M, Prieto P, Blaauboer BJ, Bois FY, Boobis A, Brochot C, Coecke S, Freidig A, Gundert-Remy U, Hartung T, Jacobs MN, Lavé T, Leahy DE, Lennernäs H, Loizou GD, Meek B, Pease C, Rowland M, Spendiff M, Yang J, Zeilmaker M. Bouvier d'Yvoire M, et al. Altern Lab Anim. 2007 Dec;35(6):661-71. doi: 10.1177/026119290703500606. Altern Lab Anim. 2007. PMID: 18186671 No abstract available.
Local kinetics and dynamics of xenobiotics.
Pelkonen O, Kapitulnik J, Gundert-Remy U, Boobis AR, Stockis A. Pelkonen O, et al. Crit Rev Toxicol. 2008;38(8):697-720. doi: 10.1080/10408440802194931. Crit Rev Toxicol. 2008. PMID: 18686076 Review.
366 results