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Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming.
Nat Commun. 2018 Aug 29;9(1):3506. doi: 10.1038/s41467-018-05861-7.
Nat Commun. 2018.
PMID: 30158636
Free PMC article.
Nrf2 Negatively Regulates Type I Interferon Responses and Increases Susceptibility to Herpes Genital Infection in Mice.
Gunderstofte C, Iversen MB, Peri S, Thielke A, Balachandran S, Holm CK, Olagnier D.
Gunderstofte C, et al.
Front Immunol. 2019 Sep 6;10:2101. doi: 10.3389/fimmu.2019.02101. eCollection 2019.
Front Immunol. 2019.
PMID: 31555293
Free PMC article.
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2017 Keystone Symposia at the Fairmont Banff Springs: Exploring new concepts in innate immunity and interferon signaling at the haunted castle.
Gunderstofte C, Holm CK, Olagnier D.
Gunderstofte C, et al.
Cytokine Growth Factor Rev. 2017 Jun;35:1-6. doi: 10.1016/j.cytogfr.2017.05.005. Epub 2017 May 20.
Cytokine Growth Factor Rev. 2017.
PMID: 28576287
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Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling.
Hansen AL, Buchan GJ, Rühl M, Mukai K, Salvatore SR, Ogawa E, Andersen SD, Iversen MB, Thielke AL, Gunderstofte C, Motwani M, Møller CT, Jakobsen AS, Fitzgerald KA, Roos J, Lin R, Maier TJ, Goldbach-Mansky R, Miner CA, Qian W, Miner JJ, Rigby RE, Rehwinkel J, Jakobsen MR, Arai H, Taguchi T, Schopfer FJ, Olagnier D, Holm CK.
Hansen AL, et al. Among authors: gunderstofte c.
Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7768-E7775. doi: 10.1073/pnas.1806239115. Epub 2018 Jul 30.
Proc Natl Acad Sci U S A. 2018.
PMID: 30061387
Free PMC article.
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