Gunawardena TNA - Search Results

1

The CFTR Mutation c.3453G > C (D1152H) Confers an Anion Selectivity Defect in Primary Airway Tissue that Can Be Rescued by Ivacaftor.

Laselva O, Moraes TJ, He G, Bartlett C, Szàrics I, Ouyang H, Gunawardena TNA, Strug L, Bear CE, Gonska T. Laselva O, et al. Among authors: gunawardena tna. J Pers Med. 2020 May 13;10(2):40. doi: 10.3390/jpm10020040. J Pers Med. 2020. PMID: 32414100 Free PMC article.

2

Functional rescue of c.3846G>A (W1282X) in patient-derived nasal cultures achieved by inhibition of nonsense mediated decay and protein modulators with complementary mechanisms of action.

Laselva O, Eckford PD, Bartlett C, Ouyang H, Gunawardena TN, Gonska T, Moraes TJ, Bear CE. Laselva O, et al. J Cyst Fibros. 2020 Sep;19(5):717-727. doi: 10.1016/j.jcf.2019.12.001. Epub 2019 Dec 9. J Cyst Fibros. 2020. PMID: 31831337 Free article.

3

A helper-dependent adenoviral vector rescues CFTR to wild-type functional levels in cystic fibrosis epithelial cells harbouring class I mutations.

Cao H, Ouyang H, Laselva O, Bartlett C, Zhou ZP, Duan C, Gunawardena T, Avolio J, Bear CE, Gonska T, Hu J, Moraes TJ. Cao H, et al. Eur Respir J. 2020 Nov 12;56(5):2000205. doi: 10.1183/13993003.00205-2020. Print 2020 Nov. Eur Respir J. 2020. PMID: 32457197 Free article.

4

Emerging preclinical modulators developed for F508del-CFTR have the potential to be effective for ORKAMBI resistant processing mutants.

Laselva O, Bartlett C, Popa A, Ouyang H, Gunawardena TNA, Gonska T, Moraes TJ, Bear CE. Laselva O, et al. Among authors: gunawardena tna. J Cyst Fibros. 2021 Jan;20(1):106-119. doi: 10.1016/j.jcf.2020.07.015. Epub 2020 Jul 30. J Cyst Fibros. 2021. PMID: 32741662 Free article.

5

Preclinical Studies of a Rare CF-Causing Mutation in the Second Nucleotide Binding Domain (c.3700A>G) Show Robust Functional Rescue in Primary Nasal Cultures by Novel CFTR Modulators.

Laselva O, McCormack J, Bartlett C, Ip W, Gunawardena TNA, Ouyang H, Eckford PDW, Gonska T, Moraes TJ, Bear CE. Laselva O, et al. Among authors: gunawardena tna. J Pers Med. 2020 Nov 5;10(4):209. doi: 10.3390/jpm10040209. J Pers Med. 2020. PMID: 33167369 Free PMC article.

6

Rescue of multiple class II CFTR mutations by elexacaftor+tezacaftor+ivacaftor mediated in part by the dual activities of elexacaftor as both corrector and potentiator.

Laselva O, Bartlett C, Gunawardena TNA, Ouyang H, Eckford PDW, Moraes TJ, Bear CE, Gonska T. Laselva O, et al. Among authors: gunawardena tna. Eur Respir J. 2021 Jun 17;57(6):2002774. doi: 10.1183/13993003.02774-2020. Print 2021 Jun. Eur Respir J. 2021. PMID: 33303536 Free PMC article.

7

A new platform for high-throughput therapy testing on iPSC-derived lung progenitor cells from cystic fibrosis patients.

Jiang JX, Wellhauser L, Laselva O, Utkina I, Bozoky Z, Gunawardena T, Ngan Z, Xia S, Di Paola M, Eckford PDW, Ratjen F, Moraes TJ, Parkinson J, Wong AP, Bear CE. Jiang JX, et al. Stem Cell Reports. 2021 Nov 9;16(11):2825-2837. doi: 10.1016/j.stemcr.2021.09.020. Epub 2021 Oct 21. Stem Cell Reports. 2021. PMID: 34678210 Free PMC article.

8

Modulator Therapy in Cystic Fibrosis Patients with cis Variants in F508del Complex Allele: A Short-Term Observational Case Series.

Terlizzi V, Centrone C, Ferrari B, Castellani C, Gunawardena TNA, Taccetti G, Laselva O. Terlizzi V, et al. Among authors: gunawardena tna. J Pers Med. 2022 Aug 31;12(9):1421. doi: 10.3390/jpm12091421. J Pers Med. 2022. PMID: 36143206 Free PMC article.

9

Correlation of Electrophysiological and Fluorescence-Based Measurements of Modulator Efficacy in Nasal Epithelial Cultures Derived from People with Cystic Fibrosis.

Gunawardena TNA, Bozóky Z, Bartlett C, Ouyang H, Eckford PDW, Moraes TJ, Ratjen F, Gonska T, Bear CE. Gunawardena TNA, et al. Cells. 2023 Apr 17;12(8):1174. doi: 10.3390/cells12081174. Cells. 2023. PMID: 37190083 Free PMC article.

10

Clinical and functional efficacy of elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis carrying the N1303K mutation.

Sadras I, Kerem E, Livnat G, Sarouk I, Breuer O, Reiter J, Gileles-Hillel A, Inbar O, Cohen M, Gamliel A, Stanleigh N, Gunawardena T, Bartlett C, Gonska T, Moraes T, Eckford PDW, Bear CE, Ratjen F, Kerem B, Wilschanski M, Shteinberg M, Cohen-Cymberknoh M. Sadras I, et al. J Cyst Fibros. 2023 Nov;22(6):1062-1069. doi: 10.1016/j.jcf.2023.06.001. Epub 2023 Jun 16. J Cyst Fibros. 2023. PMID: 37331863

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

13 results

Search Page