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Proton transfer activity of the reconstituted Mycobacterium tuberculosis MmpL3 is modulated by substrate mimics and inhibitors.
Stevens CM, Babii SO, Pandya AN, Li W, Li Y, Mehla J, Scott R, Hegde P, Prathipati PK, Acharya A, Liu J, Gumbart JC, North J, Jackson M, Zgurskaya HI. Stevens CM, et al. Among authors: gumbart jc. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2113963119. doi: 10.1073/pnas.2113963119. Epub 2022 Jul 19. Proc Natl Acad Sci U S A. 2022. PMID: 35858440 Free PMC article.
Conformational Dynamics of AcrA Govern Multidrug Efflux Pump Assembly.
Hazel AJ, Abdali N, Leus IV, Parks JM, Smith JC, Zgurskaya HI, Gumbart JC. Hazel AJ, et al. Among authors: gumbart jc. ACS Infect Dis. 2019 Nov 8;5(11):1926-1935. doi: 10.1021/acsinfecdis.9b00273. Epub 2019 Sep 26. ACS Infect Dis. 2019. PMID: 31517484 Free PMC article.
Inward-facing glycine residues create sharp turns in β-barrel membrane proteins.
Zhang Z, Ryoo D, Balusek C, Acharya A, Rydmark MO, Linke D, Gumbart JC. Zhang Z, et al. Among authors: gumbart jc. Biochim Biophys Acta Biomembr. 2021 Oct 1;1863(10):183662. doi: 10.1016/j.bbamem.2021.183662. Epub 2021 Jun 17. Biochim Biophys Acta Biomembr. 2021. PMID: 34097860 Free PMC article.
149 results