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Ambra1 modulates the tumor immune microenvironment and response to PD-1 blockade in melanoma.
Frias A, Di Leo L, Antoranz A, Nazerai L, Carretta M, Bodemeyer V, Pagliuca C, Dahl C, Claps G, Mandelli GE, Andhari MD, Pacheco MP, Sauter T, Robert C, Guldberg P, Madsen DH, Cecconi F, Bosisio FM, De Zio D. Frias A, et al. Among authors: guldberg p. J Immunother Cancer. 2023 Mar;11(3):e006389. doi: 10.1136/jitc-2022-006389. J Immunother Cancer. 2023. PMID: 36868570 Free PMC article.
DNA methyltransferase inhibition promotes recruitment of myeloid-derived suppressor cells to the tumor microenvironment through induction of tumor cell-intrinsic interleukin-1.
Traynor S, Terp MG, Nielsen AY, Guldberg P, Jakobsen M, Pedersen PG, Gammelgaard OL, Pedersen CB, Pedersen MT, Rattenborg S, Ditzel HJ, Gjerstorff MF. Traynor S, et al. Among authors: guldberg p. Cancer Lett. 2023 Jan 1;552:215982. doi: 10.1016/j.canlet.2022.215982. Epub 2022 Oct 27. Cancer Lett. 2023. PMID: 36309209 Free article.
NAD+ regulates nucleotide metabolism and genomic DNA replication.
Munk SHN, Merchut-Maya JM, Adelantado Rubio A, Hall A, Pappas G, Milletti G, Lee M, Johnsen LG, Guldberg P, Bartek J, Maya-Mendoza A. Munk SHN, et al. Among authors: guldberg p. Nat Cell Biol. 2023 Dec;25(12):1774-1786. doi: 10.1038/s41556-023-01280-z. Epub 2023 Nov 13. Nat Cell Biol. 2023. PMID: 37957325 Free PMC article.
Age-related differences in cancer biology in older patients.
Gammelgaard OL, Guldberg P, Gjerstorff MF, Ditzel HJ. Gammelgaard OL, et al. Among authors: guldberg p. Ugeskr Laeger. 2024 Jan 22;186(4):V06230375. doi: 10.61409/V06230375. Ugeskr Laeger. 2024. PMID: 38305317 Free article. Review. Danish.
Adoptive cell transfer therapy with ex vivo primed peripheral lymphocytes in combination with anti-PDL1 therapy effectively inhibits triple-negative breast cancer growth and metastasis.
Gammelgaard OL, Terp MG, Kirkin AF, Johansen S, Traynor S, Vever H, Guldberg P, Kodahl AR, Gjerstorff MF, Ditzel HJ. Gammelgaard OL, et al. Among authors: guldberg p. Mol Cancer. 2024 Jan 6;23(1):6. doi: 10.1186/s12943-023-01914-8. Mol Cancer. 2024. PMID: 38184565 Free PMC article.
BladMetrix: a novel urine DNA methylation test with high accuracy for detection of bladder cancer in hematuria patients.
Pharo HD, Jeanmougin M, Ager-Wick E, Vedeld HM, Sørbø AK, Dahl C, Larsen LK, Honne H, Brandt-Winge S, Five MB, Monteiro-Reis S, Henrique R, Jeronimo C, Steven K, Wahlqvist R, Guldberg P, Lind GE. Pharo HD, et al. Among authors: guldberg p. Clin Epigenetics. 2022 Sep 17;14(1):115. doi: 10.1186/s13148-022-01335-2. Clin Epigenetics. 2022. PMID: 36115961 Free PMC article.
Loss of Ambra1 promotes melanoma growth and invasion.
Di Leo L, Bodemeyer V, Bosisio FM, Claps G, Carretta M, Rizza S, Faienza F, Frias A, Khan S, Bordi M, Pacheco MP, Di Martino J, Bravo-Cordero JJ, Daniel CJ, Sears RC, Donia M, Madsen DH, Guldberg P, Filomeni G, Sauter T, Robert C, De Zio D, Cecconi F. Di Leo L, et al. Among authors: guldberg p. Nat Commun. 2021 May 5;12(1):2550. doi: 10.1038/s41467-021-22772-2. Nat Commun. 2021. PMID: 33953176 Free PMC article.
The Cancer/Testis Antigen Gene VCX2 Is Rarely Expressed in Malignancies but Can Be Epigenetically Activated Using DNA Methyltransferase and Histone Deacetylase Inhibitors.
Jakobsen MK, Traynor S, Stæhr M, Duijf PG, Nielsen AY, Terp MG, Pedersen CB, Guldberg P, Ditzel HJ, Gjerstorff MF. Jakobsen MK, et al. Among authors: guldberg p. Front Oncol. 2021 Feb 9;10:584024. doi: 10.3389/fonc.2020.584024. eCollection 2020. Front Oncol. 2021. PMID: 33634013 Free PMC article.
208 results