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Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression.
Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD. Varela-Eirín M, et al. Among authors: guitian caamano a. Cell Death Dis. 2022 Aug 5;13(8):681. doi: 10.1038/s41419-022-05089-w. Cell Death Dis. 2022. PMID: 35931686 Free PMC article.
Targeting of chondrocyte plasticity via connexin43 modulation attenuates cellular senescence and fosters a pro-regenerative environment in osteoarthritis.
Varela-Eirín M, Varela-Vázquez A, Guitián-Caamaño A, Paíno CL, Mato V, Largo R, Aasen T, Tabernero A, Fonseca E, Kandouz M, Caeiro JR, Blanco A, Mayán MD. Varela-Eirín M, et al. Among authors: guitian caamano a. Cell Death Dis. 2018 Dec 5;9(12):1166. doi: 10.1038/s41419-018-1225-2. Cell Death Dis. 2018. PMID: 30518918 Free PMC article.
Emerging functions and clinical prospects of connexins and pannexins in melanoma.
Varela-Vázquez A, Guitián-Caamaño A, Carpintero-Fernandez P, Fonseca E, Sayedyahossein S, Aasen T, Penuela S, Mayán MD. Varela-Vázquez A, et al. Among authors: guitian caamano a. Biochim Biophys Acta Rev Cancer. 2020 Aug;1874(1):188380. doi: 10.1016/j.bbcan.2020.188380. Epub 2020 May 24. Biochim Biophys Acta Rev Cancer. 2020. PMID: 32461135 Free article. Review.