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Lactococcus lactis expressing either Staphylococcus aureus fibronectin-binding protein A or Listeria monocytogenes internalin A can efficiently internalize and deliver DNA in human epithelial cells.
Innocentin S, Guimarães V, Miyoshi A, Azevedo V, Langella P, Chatel JM, Lefèvre F. Innocentin S, et al. Among authors: guimaraes v. Appl Environ Microbiol. 2009 Jul;75(14):4870-8. doi: 10.1128/AEM.00825-09. Epub 2009 May 29. Appl Environ Microbiol. 2009. PMID: 19482952 Free PMC article.
A novel mucosal vaccine based on live Lactococci expressing E7 antigen and IL-12 induces systemic and mucosal immune responses and protects mice against human papillomavirus type 16-induced tumors.
Bermúdez-Humarán LG, Cortes-Perez NG, Lefèvre F, Guimarães V, Rabot S, Alcocer-Gonzalez JM, Gratadoux JJ, Rodriguez-Padilla C, Tamez-Guerra RS, Corthier G, Gruss A, Langella P. Bermúdez-Humarán LG, et al. Among authors: guimaraes v. J Immunol. 2005 Dec 1;175(11):7297-302. doi: 10.4049/jimmunol.175.11.7297. J Immunol. 2005. PMID: 16301635
A new plasmid vector for DNA delivery using lactococci.
Guimarães V, Innocentin S, Chatel JM, Lefèvre F, Langella P, Azevedo V, Miyoshi A. Guimarães V, et al. Genet Vaccines Ther. 2009 Feb 10;7:4. doi: 10.1186/1479-0556-7-4. Genet Vaccines Ther. 2009. PMID: 19208231 Free PMC article.
Protein secretion in Lactococcus lactis : an efficient way to increase the overall heterologous protein production.
Le Loir Y, Azevedo V, Oliveira SC, Freitas DA, Miyoshi A, Bermúdez-Humarán LG, Nouaille S, Ribeiro LA, Leclercq S, Gabriel JE, Guimaraes VD, Oliveira MN, Charlier C, Gautier M, Langella P. Le Loir Y, et al. Among authors: guimaraes vd. Microb Cell Fact. 2005 Jan 4;4(1):2. doi: 10.1186/1475-2859-4-2. Microb Cell Fact. 2005. PMID: 15631634 Free PMC article.
Enhancing RECK Expression Through miR-21 Inhibition: A Promising Strategy for Bladder Carcinoma Control.
Dos Santos PRM, da Silva Gomes PR, Romão P, Maluf FC, Guimarães VR, Candido P, Gonçalves GL, de Camargo JA, Dos Santos GA, Silva I, Leite KRM, Nahas W, Reis ST, Pimenta R, Viana NI. Dos Santos PRM, et al. Among authors: guimaraes vr. Biochem Genet. 2024 Mar 24. doi: 10.1007/s10528-024-10714-8. Online ahead of print. Biochem Genet. 2024. PMID: 38522065
255 results