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Interaction between hormone-sensitive lipase and ChREBP in fat cells controls insulin sensitivity.
Morigny P, Houssier M, Mairal A, Ghilain C, Mouisel E, Benhamed F, Masri B, Recazens E, Denechaud PD, Tavernier G, Caspar-Bauguil S, Virtue S, Sramkova V, Monbrun L, Mazars A, Zanoun M, Guilmeau S, Barquissau V, Beuzelin D, Bonnel S, Marques M, Monge-Roffarello B, Lefort C, Fielding B, Sulpice T, Astrup A, Payrastre B, Bertrand-Michel J, Meugnier E, Ligat L, Lopez F, Guillou H, Ling C, Holm C, Rabasa-Lhoret R, Saris WHM, Stich V, Arner P, Rydén M, Moro C, Viguerie N, Harms M, Hallén S, Vidal-Puig A, Vidal H, Postic C, Langin D. Morigny P, et al. Among authors: guillou h. Nat Metab. 2019 Jan;1(1):133-146. doi: 10.1038/s42255-018-0007-6. Epub 2018 Dec 3. Nat Metab. 2019. PMID: 32694809
Is Crohn's creeping fat an adipose tissue?
Olivier I, Théodorou V, Valet P, Castan-Laurell I, Guillou H, Bertrand-Michel J, Cartier C, Bezirard V, Ducroc R, Segain JP, Portier G, Kirzin S, Moreau J, Duffas JP, Ferrier L, Eutamène H. Olivier I, et al. Among authors: guillou h. Inflamm Bowel Dis. 2011 Mar;17(3):747-57. doi: 10.1002/ibd.21413. Inflamm Bowel Dis. 2011. PMID: 20684014
P-glycoprotein dysfunction contributes to hepatic steatosis and obesity in mice.
Foucaud-Vignault M, Soayfane Z, Ménez C, Bertrand-Michel J, Martin PG, Guillou H, Collet X, Lespine A. Foucaud-Vignault M, et al. Among authors: guillou h. PLoS One. 2011;6(9):e23614. doi: 10.1371/journal.pone.0023614. Epub 2011 Sep 16. PLoS One. 2011. PMID: 21949682 Free PMC article.
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans.
Benhamed F, Denechaud PD, Lemoine M, Robichon C, Moldes M, Bertrand-Michel J, Ratziu V, Serfaty L, Housset C, Capeau J, Girard J, Guillou H, Postic C. Benhamed F, et al. Among authors: guillou h. J Clin Invest. 2012 Jun;122(6):2176-94. doi: 10.1172/JCI41636. Epub 2012 May 1. J Clin Invest. 2012. PMID: 22546860 Free PMC article. Clinical Trial.
A systems biology approach to the hepatic role of the oxysterol receptor LXR in the regulation of lipogenesis highlights a cross-talk with PPARα.
Ducheix S, Podechard N, Lasserre F, Polizzi A, Pommier A, Murzilli S, Di Lisio C, D'Amore S, Bertrand-Michel J, Montagner A, Pineau T, Loiseau N, Lobaccaro JM, Martin PG, Guillou H. Ducheix S, et al. Among authors: guillou h. Biochimie. 2013 Mar;95(3):556-67. doi: 10.1016/j.biochi.2012.09.028. Epub 2012 Oct 10. Biochimie. 2013. PMID: 23063693
Essential fatty acids deficiency promotes lipogenic gene expression and hepatic steatosis through the liver X receptor.
Ducheix S, Montagner A, Polizzi A, Lasserre F, Marmugi A, Bertrand-Michel J, Podechard N, Al Saati T, Chétiveaux M, Baron S, Boué J, Dietrich G, Mselli-Lakhal L, Costet P, Lobaccaro JM, Pineau T, Theodorou V, Postic C, Martin PG, Guillou H. Ducheix S, et al. Among authors: guillou h. J Hepatol. 2013 May;58(5):984-92. doi: 10.1016/j.jhep.2013.01.006. Epub 2013 Jan 16. J Hepatol. 2013. PMID: 23333450
141 results