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Insights into the role of hepatocyte PPARα activity in response to fasting.
Régnier M, Polizzi A, Lippi Y, Fouché E, Michel G, Lukowicz C, Smati S, Marrot A, Lasserre F, Naylies C, Batut A, Viars F, Bertrand-Michel J, Postic C, Loiseau N, Wahli W, Guillou H, Montagner A. Régnier M, et al. Among authors: guillou h. Mol Cell Endocrinol. 2018 Aug 15;471:75-88. doi: 10.1016/j.mce.2017.07.035. Epub 2017 Jul 31. Mol Cell Endocrinol. 2018. PMID: 28774777
Identification of potential mechanisms of toxicity after di-(2-ethylhexyl)-phthalate (DEHP) adult exposure in the liver using a systems biology approach.
Eveillard A, Lasserre F, de Tayrac M, Polizzi A, Claus S, Canlet C, Mselli-Lakhal L, Gotardi G, Paris A, Guillou H, Martin PG, Pineau T. Eveillard A, et al. Among authors: guillou h. Toxicol Appl Pharmacol. 2009 May 1;236(3):282-92. doi: 10.1016/j.taap.2009.02.008. Epub 2009 Feb 23. Toxicol Appl Pharmacol. 2009. PMID: 19245819
P-glycoprotein dysfunction contributes to hepatic steatosis and obesity in mice.
Foucaud-Vignault M, Soayfane Z, Ménez C, Bertrand-Michel J, Martin PG, Guillou H, Collet X, Lespine A. Foucaud-Vignault M, et al. Among authors: guillou h. PLoS One. 2011;6(9):e23614. doi: 10.1371/journal.pone.0023614. Epub 2011 Sep 16. PLoS One. 2011. PMID: 21949682 Free PMC article.
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans.
Benhamed F, Denechaud PD, Lemoine M, Robichon C, Moldes M, Bertrand-Michel J, Ratziu V, Serfaty L, Housset C, Capeau J, Girard J, Guillou H, Postic C. Benhamed F, et al. Among authors: guillou h. J Clin Invest. 2012 Jun;122(6):2176-94. doi: 10.1172/JCI41636. Epub 2012 May 1. J Clin Invest. 2012. PMID: 22546860 Free PMC article. Clinical Trial.
A systems biology approach to the hepatic role of the oxysterol receptor LXR in the regulation of lipogenesis highlights a cross-talk with PPARα.
Ducheix S, Podechard N, Lasserre F, Polizzi A, Pommier A, Murzilli S, Di Lisio C, D'Amore S, Bertrand-Michel J, Montagner A, Pineau T, Loiseau N, Lobaccaro JM, Martin PG, Guillou H. Ducheix S, et al. Among authors: guillou h. Biochimie. 2013 Mar;95(3):556-67. doi: 10.1016/j.biochi.2012.09.028. Epub 2012 Oct 10. Biochimie. 2013. PMID: 23063693
141 results